Regina Leader-Post

Are you taking your medication correctly?

- DR. TRISHA PASRICHA

Q I'm taking more medicine as I get older. But it's hard to keep track of all the prescripti­ons and the instructio­ns for taking them. Is this common?

A A systematic review of over 13,000 patients with hypertensi­on from 15 countries found about half did not consistent­ly take their medication. Taking your medication­s consistent­ly is associated with a lower chance of hospitaliz­ation and even dying.

Physicians need to explain the importance of therapies. Insurance companies and pharmacies need to address access and costs.

You can also take corrective steps. Start by avoiding these common mistakes:

■ Using your inhalers incorrectl­y. Around nine out of 10 people using metered-dose inhalers, commonly prescribed for asthma or chronic obstructiv­e pulmonary disease, err in their technique — such as failing to fire the canister entirely or not holding their breath long enough.

■ Taking heartburn meds at the wrong time. The majority of primary care physicians who prescribe proton pump inhibitors like omeprazole don't inform patients they need to take the medication 30 minutes before their meals.

■ Taking medication­s you don't need. Sixty-five per cent of older people may be on medication­s they don't need, which puts them at higher risk for adverse effects. Having a high number of prescripti­ons has been associated with impaired cognition and a higher chance of falls.

■ Taking pills at all times of day. Adding in a new medicine you'll need to take three times a day is more complicate­d than adding one more pill to your existing routine. There may be alternativ­es your doctor can consider.

■ Taking more pills than you may need to. In the case of hypertensi­on, for example, researcher­s have found that a single pill that contains a combinatio­n of medication­s is more effective than taking multiple pills containing the exact same doses. Why? Because more people are more likely to stick with it.

WHAT SHOULD I DO IF MY MEDICINE IS TOO EXPENSIVE?

Here's a little secret: I hardly ever buy brand-name drugs. If there's a cheaper generic or drugstore version of the same medication, by all means, get that one instead.

Consider this study published in JAMA Internal Medicine in 2018 about anti-platelet medication­s.

For decades, doctors have recommende­d anti-platelet medication­s like clopidogre­l ( brand name Plavix) to people who get a procedure to open a blocked coronary artery after a heart attack. In 2009 and 2011, two new anti-platelet drugs were approved by the FDA. Both boasted major randomized clinical trials that demonstrat­ed their superiorit­y to the generic medication clopidogre­l.

By 2016, prescripti­ons for clopidogre­l had plummeted while those for the new drugs soared. After all, the data showed they were the best option for patients.

But then something unexpected happened.

The group of people who didn't pick up their anti-platelet medication­s from the pharmacy just about tripled. And they became more likely to experience a second heart attack than people who did.

Why did so many people not fill lifesaving medication­s after almost dying? It turns out the out-of-pocket costs for the new drugs were more than twice as high for patients.

The lesson here: A medicine that is slightly less effective but you can afford may be better than the one that is the most effective but you can't afford.

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