Saskatoon StarPhoenix

Doctor worked to unlock secrets of human brain

- TIM SWITZER

Dr. Abram Hoffer once wrote: “I give my critics full credit for having delayed the full introducti­on of orthomolec­ular medicine into the medical world and for having denied life, health and happiness for innumerabl­e patients.”

It seems the perfect glimpse into the mind of the Saskatchew­an man who gained knowledge of so many others’ brains while facing doubt from many in the world of psychiatry.

Born in 1917 in a farmhouse in southwest Saskatchew­an, Hoffer would go on to the universiti­es of Minnesota and Toronto before returning to his home province in 1950 to organize a provincial research division in psychiatry.

It was during that time he teamed with England’s Dr. Humphry Osmond to discover treatments for schizophre­nia, high cholestero­l and alcoholism.

The pair found LSD could recreate the symptoms of schizophre­nia and studied the physiology of a person while on the drug, leading to the discovery of adrenochro­me (oxidized excess adrenalin with psychedeli­c properties that they suggested could induce schizophre­nia).

They had much success treating schizophre­nics through the use of high doses of anti-oxidants niacin and vitamin C.

Hoffer and Osmond also treated alcoholics with LSD, finding the drug could simulate the lifechangi­ng hallucinat­ions drinkers could have that led them to stop drinking. Despite criticism from the medical community, schizophre­nics would sometimes show up at the door of Hoffer’s Saskatoon home asking for help.

In recent years, more research into oxidizatio­n and vitamin use has been undertaken to learn more about treating diseases of the brain.

Hoffer died in Victoria in 2009 at the age of 91.

As we celebrate Canada’s 150th birthday in 2017, the Leader-Post and StarPhoeni­x are telling the stories of 150 Saskatchew­an people who helped shape the nation. Send your suggestion­s or feedback to sask150@postmedia.com.

 ?? DEBRA BRASH/VICTORIA TIMES COLONIST ?? Dr. Abram Hoffer maintained the two most important vitamins are niacin and vitamin C.
DEBRA BRASH/VICTORIA TIMES COLONIST Dr. Abram Hoffer maintained the two most important vitamins are niacin and vitamin C.

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