The Guardian (Charlottetown)

EFFECTIVE AND SAFE

Parents need to make sure children get vaccinated according to the recommende­d schedule

- Dr. David Wong

Measles vaccine, like all vaccines available for children in Canada necessary to protect from infections, says columnist

Dear Dr. Wong: I got measles when I was 16. One of my classmates went to Europe and brought the virus back to school. I was never vaccinated and got very sick.

My parents didn’t believe in vaccinatio­n; they thought it was unnecessar­y. Now, I am the mother of two children, one and three years of age. They never received any vaccine either; I guess I am still being influenced by my parents’ opinion.

My husband is urging me to get them vaccinated; he is worried that they can get sick with germs that are preventabl­e through vaccinatio­n. I heard that some schools are not allowing students to attend if they didn’t get measles vaccine.

0Is there any proof that measles vaccine is useful and safe?

Answer. Yes, the measles vaccine is effective and safe. In fact, all vaccines available for children in this country are necessary to protect them from infections that are serious and sometimes fatal. Let me explain to you in more detail here.

We are surrounded by germs all the time, both bacteria and viruses. From the moment of birth, these germs try to gain access to our body and cause infections. When we have a cut, germs on the skin enter our tissues and blood. Our body’s immune system isolates the germs locally and sends white blood cells to kill these bacteria. We can recover from most minor wounds without the need of antibiotic­s.

At the same time, our immune system can recognize the germs and produce antibodies against them. These involve memory cells and antibodypr­oducing cells of the immune system. They allow the body to fight the same germs faster and more effectivel­y the next time around. The same is true for viruses. We have memory cells and antibody-producing cells that can fight viruses that have infected us, even many years ago. This part of our immune system is very important for our health and survival.

Measles is a unique virus. In addition to causing fever and rash, it infects many organs in the body. It also infects our immune system, destroying memory cells as well as

antibody-producing cells.

A recent research publicatio­n in the journal Science documented the serious harm of the measles virus. Unvaccinat­ed children infected with measles virus lost a great deal of their memory cells and antibody-producing cells in their immune system. As a result, when they encountere­d bacteria and viruses that have infected them before, they have no ability to respond quickly and effectivel­y; they have to fight these infections all over again.

This explains the longstandi­ng observatio­n that measles infection weakens our immune system. Many children die within a few years after they have recovered from measles infection; they die from other infections that they are normally able to fight. Pneumonia is a common complicati­on of measles that kills many children in countries that don’t have a good healthcare system like Canada.

Measles vaccine was one of the earliest vaccines developed by scientists half a century ago; it is also one of the safest vaccines that we have. The measles virus was “tamed” in the laboratory. After vaccinatio­n, it causes a mild infection and induces both memory and antibodies against the measles virus.

Measles vaccine is now given as part of the MMRV (measles, mumps, rubella and varicella) vaccine. In addition to preventing measles infection, it prevents a person from a weakening of the immune system and other serious infections. The benefit of the measles vaccine is far greater than preventing measles alone.

Vaccines are tested extensivel­y to make sure that they are effective and safe. There can be mild side effects, especially local pain and fever.

There is also ongoing monitoring of vaccine safety and efficacy by Health Canada.

I hope you have a better understand­ing of the importance of measles vaccine and its benefits. Actually, all vaccines that the government recommends are important and safe; different vaccines protect us in different ways. Our government spends a lot of money on vaccinatio­n to keep us safe and healthy. We should make sure that our children get vaccinated according to the recommende­d schedule.

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