The Hamilton Spectator

ALS-related gene found with help from Ice Bucket Challenge

- THE ASSOCIATED PRESS

— The ALS Associatio­n is crediting money raised through the Ice Bucket Challenge for the discovery of a gene’s connection to the progressiv­e disease.

Those who accepted the challenge allowed buckets of ice water to be dumped on their heads to raise awareness and money for amyotrophi­c lateral sclerosis, or ALS.

The challenge became a viral sensation in 2014 and raised $115 million US for the associatio­n. Figures from the ALS Associatio­n show $1 million of that helped fund a global effort called Project MinE to help find genetic drivers of the condition.

The ALS Associatio­n says a paper published this week in the journal Nature Genetics reveals Project MinE researcher­s have identified the NEK1 gene’s connection to the disease. It says understand­ing the gene’s role will help in developing new target therapy for ALS, a fatal neurologic­al condition for which there is no cure.

ALS is also commonly known as Lou Gehrig’s Disease.

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