The Miracle

No additional CoViD-19 deaths in B.C. for 6th straight day

-

VANCOUVER -- For the sixth consecutiv­e day, British Columbia has seen no additional deaths from COVID-19, health officials announced Thursday.

They also announced eight additional testpositi­ve cases of the virus, bringing the total identified since the coronaviru­s pandemic began to 2,783.

Of that total, there are 190 active cases of the virus, including 10 people who are hospitaliz­ed, five of whom are in intensive care.

You’re describing systemic failure from a number of institutio­ns. How did we get to this point? In 2009, when there was pandemic influenza, the prevailing thought was that it was just too complicate­d to do proper studies in the midst of an emergency. In retrospect, there were so many missed opportunit­ies. In Ebola, 2014, this changed, thanks a lot to the U.S., which insisted that we adhere to high standards of science. The U.S. government helped lead the efforts to conduct proper studies, not only for vaccines, but also for therapeuti­cs against Ebola. That was a paradigm shift.

Going back to the 2009 pandemic flu, the FDA issued an emergency use authorizat­ion for peramivir, an investigat­ional flu drug that was at an advanced stage of clinical developmen­t. The U.S. government back then did not think it could do a randomized controlled study in the middle of a pandemic. Because there was tremendous demand for this drug, it turned out that it took two more years for the company to actually accrue enough patients to enroll in the proper clinical studies that actually demonstrat­ed that the drug had no value in the population. It didn’t really help the population for which we issued the emergency authorizat­ion. Imagine how quickly this could have been demonstrat­ed if it had been done in the pandemic, given how many cases were there.

I thought we had moved on. So it was so surprising to me to have the Covid pandemic and see the number of studies, not just in the U.S., but globally, that were designed in such a manner that do not yield results that can be interprete­d, neither with respect to safety or efficacy. And then you end up with the pile of confusion.

How much of this is because the government officials you described as stepping up in Ebola are not doing what they should now?

 ??  ??

Newspapers in English

Newspapers from Canada