The Province

ADHD is a brain disorder that can be treated

- DIANE MCINTOSH, DERRYCK SMITH, DON DUNCAN, DOROTHY REDDY AND JULIA HUNTER

With each instalment of their $10-million, unscientif­ic, “review of the evidence,” we hope that our medical colleagues will be moved to act and demand that the Therapeuti­cs Initiative be de-funded again.

This time, the Initiative’s unnamed group of “75 experts and primarycar­e physicians” took aim at the treatment of attention deficit hyperactiv­ity disorder (ADHD), cherry-picking research and grossly misreprese­nting the evidence to support their nefarious claims and prejudices.

Reading the Initiative’s assertion that “teachers, parents and physicians are medicalizi­ng a social rather than a medical problem” was a real blast from the past ... reminiscen­t of blaming mothers for schizophre­nia and labelling wounded warriors with PTSD as having LMF — that’s Low Moral Fibre.

The debate concerning whether it’s safe and appropriat­e to treat ADHD is the psychiatry equivalent of the childhood vaccinatio­n debate. In both cases, the science is abundant and unequivoca­l. The decision not to vaccinate poses a personal risk to the child but also has societal implicatio­ns, putting vulnerable children who cannot be vaccinated at risk.

Likewise, there is an abundance of high-quality evidence demonstrat­ing that ADHD is a brain disorder and that a failure to diagnose and treat ADHD can have serious personal and societal implicatio­ns.

ADHD is a neuro-developmen­tal disorder that affects up to eight per cent of children and four per cent of adults. While it was once considered a childhood disorder, with enhanced brain imaging research we now know that at least half of adults who had childhood ADHD continue to experience significan­t symptoms and functional impairment.

The Therapeuti­cs Initiative suggests ADHD is nothing more than a “social” issue, or a normal variant of childhood behaviour associated with starting school too early. Yet there is an abundance of replicated research evidence proving that children and adults with ADHD have widespread brain structure and size difference­s that are directly correlated with the symptoms of ADHD. It is also the most inheritabl­e psychiatri­c disorder.

The diagnosis of ADHD may include symptoms of inattentio­n, hyperactiv­ity, and impulsivit­y, but also includes an inability to meet age-appropriat­e functional demands at home, school, or work.

ADHD is not associated with intellectu­al impairment, but children with ADHD often struggle academical­ly and socially because of the delayed developmen­t of critical brain areas. In school, they are told they are not living up to their potential, but often they receive a blunter assessment: you’re lazy, disruptive and frustratin­g.

Inattentiv­e kids are forgetful, lose their belongings and fail to complete tasks. They struggle to focus on topics or activities they find boring, which is why ADHD was once called “the math disorder.” They read later than their peers, and adults with ADHD often report that, due to an inability to focus, they have never been able to read anything longer than a newspaper article.

Hyperactiv­e kids are disruptive; they can’t sit still or work and play co-operativel­y. Impulsive kids can’t wait their turn, they’re intrusive and they have more serious accidents. Many children with ADHD are irritable and have explosive tempers. As a result, they struggle to make and keep friends, impacting their self-esteem which may ultimately hinder their success in adult life.

Compared with their peers without ADHD, adolescent­s with untreated ADHD are less likely to complete high school or post-secondary education, more likely to abuse illicit substances, have more driving infraction­s and serious accidents, and are more likely to have an unwanted pregnancy or a sexually transmitte­d disease. As adults, those with ADHD are more likely to be incarcerat­ed, divorced and cause a fatal car accident. Those are costly personal and societal issues.

The increased use of ADHD medication in B.C. is heartening because it suggests that more children are being diagnosed and treated. However, with only four per cent of B.C. children receiving treatment, ADHD is still under-diagnosed and often goes untreated.

Not every person with ADHD requires medication. Talk therapy and education about ADHD are considered important first-line interventi­ons. Accommodat­ions at school, allowing more time for projects and tests, as an example, can be invaluable. However, large review studies have demonstrat­ed that those types of interventi­ons have inconsiste­nt effects on ADHD symptoms compared to medication treatments. If skills building and support are insufficie­nt, ADHD medication­s are among the most effective treatments in all of medicine and for most patients, they are very well tolerated. Because we prescribe them for children, they’re also among the most well-researched treatments in medicine. We also have a wealth of clinical experience, because we have been prescribin­g them for ADHD for more than 80 years.

Treatment for any disorder comes with risks, and every patient (or their parents) must weight those risks against the potential benefits. Parents must receive informatio­n regarding the pros and cons of any treatment from their health care provider and make an informed decision that makes sense for their child and their family.

It is the responsibi­lity of every family doctor, pediatrici­an, and psychiatri­st in B.C. to know the research evidence regarding the safety and effectiven­ess of ADHD treatments and offer that informatio­n to patients/ parents, so they can make an informed choice. Likewise, the B.C. government has a responsibi­lity to ensure that they only fund programs that improve the care British Columbians receive. The Therapeuti­cs Initiative are doing a disservice to children and youth in B.C. and Canada by presenting clinicians with biased and inaccurate informatio­n.

Doctors who read the research and actually treat patients believe that, much like the individual and societal value of vaccinatio­ns, the evidence for ADHD is unequivoca­l: it is a brain disorder that impacts a child’s developmen­t and achievemen­t and negatively impacts society. Gratifying­ly, for most of our patients, appropriat­ely treating their ADHD is beneficial for their entire family.

The fact that the Therapeuti­cs Initiative cloaks their opinions as “science” is appalling. Their newsletter would never be published in a peer review journal and yet it has now reached clinicians, and, therefore families, across Canada. Their unnamed experts are unlikely pediatrici­ans or child psychiatri­sts, which seriously undermines their ability to provide credible evidence-based guidelines for treating children and youth with ADHD.

Despite the mountains of evidence and 80-plus years of treatment experience, the Therapeuti­cs Initiative opines that ADHD is merely a “social problem” and not a medical one. The scientific evidence shows us that it is both.

Drs. Diane McIntosh, BSc Pharmacy, MD, FRCPC, psychiatri­st and clinical assistant professor, UBC; Derryck Smith, MD, FRCPC, psychiatri­st and professor emeritus, UBC; Don Duncan, MD, FRCPC, psychiatri­st and clinical assistant professor, UBC, clinical director, B.C. Interior ADHD Clinic; Dorothy Reddy, BSc, MD, FRCPC, research fellow, psychiatri­st; Julia Hunter, BSc, MSc, MD, FRCPC, psychiatri­st.

 ?? — MICHELLE BERG FILES ?? Eleven-year-old Sienna Forsberg is a top-level gymnast (Level 7 of 10 in the Junior Olympics program) at the Marion club, despite having FAS, ADHD and other intellectu­al disabiliti­es.
— MICHELLE BERG FILES Eleven-year-old Sienna Forsberg is a top-level gymnast (Level 7 of 10 in the Junior Olympics program) at the Marion club, despite having FAS, ADHD and other intellectu­al disabiliti­es.

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