The Standard (St. Catharines)

PREPARING FOR SECOND WAVE

Canada is at a ‘COVID crossroads’ and what happens is up to us

- MIA RABSON AND JIM BRONSKILL

OTTAWA — There will be a dramatic resurgence of COVID-19 cases in Canada unless people limit contact with others in coming days, the country’s chief public health officer warns.

“We don’t want it to go up a giant ski hill,” Dr. Theresa Tam said Tuesday as she described the potential for a sharp upward curve.

The Public Health Agency of Canada released its latest modelling Tuesday, predicting up to 155,795 cases and up to 9,300 deaths by early October if the current trajectory of the epidemic continues.

The message throughout the presentati­on was clear: everyone needs to act now to limit their contacts or things will get worse.

“Canada is at a crossroads and individual action to reduce contact rates will decide our path,” said a presentati­on deck released Tuesday.

Federal Health Minister Patty Hajdu echoed that advice as she urged people to think carefully before accepting invitation­s to social gatherings.

“All of us have the future in our hands,” she said.

She also said, however, that the spread of the novel coronaviru­s is not the same across the country, or even across single provinces, so determinin­g whether restrictio­ns need tightening demands a “surgical approach.”

Meanwhile, Canada has now committed more than $1 billion to buy doses of COVID-19 vaccines after securing a fifth deal with Sanofi and Glaxosmith­kline Tuesday.

Procuremen­t Minister Anita Anand said Tuesday that Canada has a deal in place to buy up to 72 million doses of their experiment­al vaccine candidate, which is just starting the second of three trial phases this month.

In all, Canada has committed $1 billion to buy at least 154 million doses of vaccines from five different companies, and most of that money will not be refunded even if the vaccines never get approved.

“We need to make a substantia­l investment in order to ensure that Canada is well positioned to secure access to the successful vaccine or vaccines,” she said.

“The way in which we are doing that is to bet on multiple horses at the same time in order to ensure that as one or more of those horses crosses the finish line, we have access to those vaccines.”

Canada has signed deals with Moderna, Pfizer, Novavax, Johnson & Johnson and now Sanofi and Glaxosmith­kline, all of which are among some of the most promising vaccines, but none of which have completed all the required clinical trials, or been approved for use in Canada.

On Sept. 3, Sanofi and Glaxosmith­kline said their vaccine candidate was going to begin Phase 1/2 trials which will test it on 440 individual­s. The hope is the vaccine will be ready for the third and final phase of trials by the end of the year, and approved for use in the first half of 2021.

Moderna has a vaccine in Phase 3 trials, and Pfizer’s is in a combined Phase 2 and 3 trial. Novavax is in a Phase 2 trial, while Johnson & Johnson is in a Phase 1/2 trial.

Most clinical trials have three phases to ensure the safety and effectiven­ess of the vaccine or drug being developed.

Each level of trials adds more volunteers on whom the drug is tested, looking for adverse health effects and whether the vaccine does cause a person to develop antibodies that can protect against COVID-19.

 ?? NATHAN DENETTE THE CANADIAN PRESS ?? A woman stretches as hundreds of people wait in line in an alleyway for hours at a COVID-19 assessment centre at St. Michael’s Hospital in Toronto on Tuesday.
NATHAN DENETTE THE CANADIAN PRESS A woman stretches as hundreds of people wait in line in an alleyway for hours at a COVID-19 assessment centre at St. Michael’s Hospital in Toronto on Tuesday.

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