The Standard (St. Catharines)

Another COVID-19 vaccine developer gets help from big pharmaceut­ical company

- RUTH BENDER

BERLIN— Chemicals and pharmaceut­icals giant Bayer AG is joining forces with Germany’s Curevac NV to support the biotech firm in its developmen­t of acovid-19 vaccine.

Under the deal, Bayer, best known for its aspirin, will support Curevac with expertise in drug developmen­t and infrastruc­ture, including supporting clinical work, regulatory affairs and supply-chain management, the two companies said. The partnershi­p is part of a now-familiar pattern in which big pharmaceut­ical companies have swooped in to help smaller players with promising Covid-19 vaccine candidates.

Pfizer Inc. and Germany’s Biontech SE co-developed the first Western-made vaccine to make it to market.

Astrazenec­a PLC, meanwhile, teamed up with the University of Oxford on a vaccine now being rolled out in the U.K., India and other markets.

Such partnershi­ps can allow smaller firms to move from developmen­t and testing to more complicate­d and expensive human trials necessary to gauge a vaccine’s effectiven­ess and safety. Should a vaccine work, a big pharmaceut­ical company’s deep pockets and expertise in manufactur­ing and distributi­on is crucial to rolling it out on a large scale.

A Curevac spokesman said production isn’t part of the Bayer agreement but that Bayer is testing whether it can also support Curevac with manufactur­ing capacities.

Bayer, which is fighting a protracted legal battle in the U.S. over its Roundup herbicides, focuses its drug developmen­t mostly on cancer, women’s health and cardiovasc­ular diseases and is currently expanding its gene-therapy business. Vaccines, however, aren’t a specialty.

Curevac, based in the southern German state of Baden-Württember­g, last month started a late-stage clinical trial of its Covid-19 vaccine candidate, called CVNCOV. It expects results by the end of the first quarter.

Curevac is backed by German biotech investor Dietmar Hopp, the German government and the Bill & Melinda Gates Foundation. Drug giant Glaxosmith­Kline PLC in July also acquired a10% stake.

In March, the German government accused the Trump administra­tion of trying to lure Curevac to the U.S.

The company uses the same gene-based technology used in the vaccine by Pfizer and BionTech and one by Moderna Inc.

The Curevac effort’s timeline is significan­tly behind those other vaccines. But soaring infection rates and a slow start to vaccinatio­n drives—in part blamed on initially low supplies—has underscore­d the continued need for new shots.

Franz-werner Haas, chief executive of Curevac, said Bayer’s expertise and infrastruc­ture will help make its vaccine “even more rapidly available to as many people as possible.”

Curevac aims to produce up to 300 million doses of the vaccine in 2021 and up to 600 million in 2022. The European Commission, the executive arm of the European Union, has secured 405 million doses of the vaccine if it gets regulator approval.

Financial terms of the deal with Bayer weren’t disclosed. Curevac will distribute and sell the vaccine in Europe, if approved, but Bayer will have options to market the shot elsewhere.

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