Times Colonist

THE ABORTION DRUG MIFEGYMISO: THE BASICS

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The abortion drug Mifegymiso is expected to hit the Canadian market next month. A look:

What is it?

Mifegymiso, also known as RU-486, is a combinatio­n of two medication­s — mifepristo­ne and misoprosto­l — used to provide a non-surgical option for early abortion.

How does it work?

Mifegymiso must be used within the first 49 days of pregnancy and will only be available with a doctor’s prescripti­on in Canada. Mifepristo­ne halts the body’s production of progestero­ne, while misoprosto­l causes the uterus to contract. This ends the pregnancy within one to two days. The process is similar to a miscarriag­e.

How is it used?

The drug is taken orally in pill form in two stages. The first step involves taking 200 mg of mifepristo­ne. The second step occurs 24 to 48 hours later, when four tablets of misoprosto­l are taken. It is up to the patient to decide when to take the tablets to allow planning so the entire process can fit within their schedule. Vaginal bleeding, cramps and the passing of some tissue commonly occurs within four hours, but in some cases may occur anywhere between 30 minutes and 48 hours after taking the misoprosto­l tablets. The bleeding lasts on average for 10 to 16 days.

When is medical attention required?

Patients should contact their doctor immediatel­y if symptoms are experience­d including prolonged heavy bleeding or severe cramping, cramping which is not improved by pain relief medication; fever, chills or malaise lasting six hours or more; any abnormal vaginal discharge; severe abdominal pain and feeling sick (including weakness, nausea, vomiting, diarrhea, abdominal discomfort, cramps, fatigue, chills) with or without a fever, more than 24 hours after taking the drug.

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