Times Colonist

Low thyroid blood levels can reduce body temperatur­e

- DR. KEITH ROACH

Dear Dr. Roach: I am an 85-yearold female with an often low body temperatur­e. I feel very warm, like I have a fever, but when I take my temperatur­e, it can be as low as 95 or 96. This has happened several times.

I’ve heard that a low temp is just the same as a high fever. I take numerous medication­s, including for my thyroid, which my doctor has had trouble regulating. What do you think? Could this be related? My normal body temp seems to run about 97.

D.C. Normal body temperatur­e varies, both during the day (morning temperatur­es are lowest), among people (normal values in young adults range from 96 F (35.6 C) to 100.8 F (38.2 C), and across ages, with older people tending to have lower body temperatur­es by 0.4 F (0.2 C). So, 97 F is not necessaril­y unusual.

However, certain medical conditions can cause the temperatur­e to be abnormally low. Low thyroid blood levels certainly can make temperatur­es lower, as can other endocrine abnormalit­ies (especially diabetes, pituitary gland problems and adrenal insufficie­ncy). Some people with chronic kidney disease have low temperatur­es. Some medication­s can affect body temperatur­e; the most common are anti-psychotic medicines, barbiturat­es (almost never used anymore) and alcohol.

There are very worrisome causes of low body temperatur­e. Sepsis, a state of abnormal body equilibriu­m related to serious infection, can present with either fever or low body temperatur­e, which probably is where you got the idea that low temperatur­e is as bad as a fever. Of course, exposure to cold can cause low temperatur­e (hypothermi­a), but that’s not what we are concerned about here.

Hopefully your doctor will get your thyroid regulated, but if your kidney function is OK, you’re not taking any of the medication­s listed and you are feeling fine, it’s much more likely that this body temperatur­e is normal for you rather than being a sign of a serious condition. Dear Dr. Roach: Fifteen months ago, I ended up in the emergency room for five hours with tachycardi­a, palpitatio­ns, elevated blood pressure and pain on my front, right side below the ribs. EKG, cardiac enzymes and chest X-ray were normal. I was discharged with no idea of the cause. The next day, my pulse/BP were normal until I sipped a cup of coffee and symptoms returned. I had cardiac stress test, sonogram and MRI of gastrointe­stinal organs. All normal.

My research indicates that my CYP1A2 enzyme (which metabolize­s caffeine in the liver) is now non-functionin­g. Is there anything I can do to get it working again? I am 74, with a 22 BMI, and my only medication is Flomax. Thank you.

M.S. I admire your research, but the way caffeine is metabolize­d in the body is more complicate­d. Some people do have unusual copies of the gene for CYP1A2, and are very sensitive to small amounts of caffeine. Other people are very tolerant, and can do fine with even large amounts of caffeine right before bed. Two other genes, ADR and PDSS2, can affect caffeine metabolism.

I don’t think your enzyme stopped working. Over time, many people become more sensitive to the effects of caffeine, and as we age, metabolism does tend to slow down, and the heart can get more irregular. If avoiding caffeine keeps your symptoms away, I would recommend that you continue to do so.

Dr. Roach regrets that he is unable to answer individual letters, but will incorporat­e them in the column whenever possible. Readers may email questions to ToYourGood­Health@med.cornell.edu

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