Times Colonist

Gender difference­s must be considered in medicine

- W. GIFFORD-JONES The Doctor Game info@docgiff.com

George Carlin, the American comedian, once remarked when referring to God: “He, and if there is a God, I am convinced He is a He because no woman could or would screw things up this badly.”

Karen Jensen, one of the world’s authoritie­s on women’s health would agree. Her new book, Women’s Health Matters, reveals how medical researcher­s and doctors screw up big time when it comes to women.

Her main point is that women are different. I say thank God for that, or as Maurice Chevalier remarked “Vive la difference!” But what is forgotten is the fact that this difference has to be considered in both research and medical treatment.

There’s a basic fact that I bet no reader knows and, I admit, I didn’t know it, either. According to the Institute of Medicine, every cell in the body has a sex. So right down to the cellular level, women are different.

But how important is this fact? It helps to explain why women are more susceptibl­e to several diseases, such as diabetes, Alzheimer’s disease, osteoporos­is, urinary tract infections, irritable bowel syndrome and depression.

How many readers know that when women eat food or take medicine, it takes twice as long for it to pass through the digestive tract than with men? But how many doctors prescribe different doses to women? Rather, it’s “one dose fits all.” But this means women experience more drug reactions than men.

It’s also been known for years that women don’t metabolize alcohol as quickly as men. I admit that these are hardly fair metabolic reactions and whoever created us failed to consider this difference. But facts are facts, and it means that women have to consume less alcohol than men.

But the difference between sexes is not just at the cellular level. For years, women have suffered more urinary tract infections (UTIs) than men because of a major anatomical difference. The urethra, the tube that carries urine from the bladder to the outside, is much shorter in women. This means that bacteria can more easily enter the bladder, triggering urinary infections. For example, in 1997, fewer than one million visits to hospital emergency department­s were made in the U.S. for this problem. In 2007, there were 8.6 million outpatient UTI visits, of which 84 per cent were made by women.

What about the No. 1 killer, heart attack? Even here, women get the short end of the stick. First of all, heart disease is more likely to go undiagnose­d in women than in men, as symptoms are often different. But even if the diagnosis is quickly made and bypass surgery required, women have a worse prognosis than men. Why? The coronary arteries in females are smaller, making the operation more technicall­y difficult.

Jensen offers only one solution to overcoming this problem. Women must become proactive and reduce their risk of disease. The best way is to start educating themselves. That way, if symptoms strike, they will be better able to determine whether the treatments they receive are safe, effective and specific to their gender.

If readers want a comprehens­ive, easy-to-read book about women’s health, Jensen’s book fits the bill. It covers everything from how stress has a major effect on adrenal glands to the fact that cholestero­l-lowering-drugs are associated with the onset of Type 2 diabetes. She looks at why more women suffer from autoimmune disease and how dementia is becoming an increasing threat to women.

There’s also informatio­n on what women should know about common hormone imbalances. And what causes low libido in women, and how natural remedies can be helpful.

And yes, Dr. Jensen, you are quite right. Women are different from men. Many difference­s make us what we are, and I say thank God for that!

Women’s Health Matters is available at health-food stores.

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