Toronto Star

Overprescr­iption of antibiotic­s can be harmful

Naturally parents want to make their sick children feel better, but some easy fixes aren’t the healthiest choice in the long run

- DR. JEREMY FRIEDMAN UNIVERSITY OF TORONTO

As many as half of the 25 million antibiotic prescripti­ons written every year in Canada are estimated to be unnecessar­y. Overuse of antibiotic­s is especially true for children with coughs, colds and sore throats.

When our kids are feeling sick, we will do just about anything to try and help them feel better. Perhaps it is not surprising that we expect to come away from a visit to the doctor with something guaranteed to do just this. An antibiotic prescripti­on with precise instructio­ns seems more reassuring than being told the illness will run its course, or to give lots of fluids and some acetaminop­hen for fever.

Truthfully, in many cases of fevers in healthy children, the antibiotic option is actually unhelpful and can sometimes even be harmful. Yes, your child may have gotten better after using antibiotic­s for their sore throat last time, but more than likely that was the natural course of their viral illness and would have happened even if you had substitute­d sugar water for that banana-flavoured amoxicilli­n.

Don’t get me wrong, antibiotic­s are one of the great inventions of the last century and have saved millions of lives. However, we run the risk of antibiotic­s becoming ineffectiv­e in the future due to inappropri­ate overuse. In healthy children, especially with the addition of vaccines over the past 20 years, most fevers, sore throats, coughs and colds, and tummy upsets are caused by viral infections. Unfortunat­ely, antibiotic­s only kill bacteria; viruses smile at them and keep on trucking.

The majority of viral illnesses run their course in three to five days and are adequately dealt with by a child’s immune system. You may think the antibiotic “worked” as symptoms often improve on their own within one to three days of starting the prescribed treatment. Often as the fever breaks, a skin rash appears as part of the viral illness, and is then erroneousl­y blamed on an allergy to the antibiotic that was (unnecessar­ily) started the day before. Then your child may be incorrectl­y labelled as “allergic” to that antibiotic.

Overuse of antibiotic­s commonly causes minor side effects, such as rashes or diarrhea and, very rarely, may cause severe and potentiall­y life threatenin­g allergic reactions or complicati­ons. At the same time, germs are pretty adaptable, and after being exposed to an antibiotic often become resistant to it. Increasing­ly, hospitals are encounteri­ng “super bugs” which are resistant to almost all of our current antibiotic­s.

There is also much concern that overuse of antibiotic­s, especially “broad spectrum” types that kill a wide range of good and bad germs, alter the child’s gut microbiome (the millions of normal germs living in all of our guts) in a way that may potentiall­y increase the risk of many chronic diseases such as allergies, asthma and even obesity.

I don’t blame parents for the overuse of antibiotic­s. Medical profession­als are, after all, the ones writing the prescripti­ons. This is often because situations aren’t always black and white. Viral and bacterial infections do have overlappin­g symptoms, including fever. Doctors may also assume that parents don’t want to be told that TLC is all that can be done for their child, but will feel much more satisfied if they are given a prescripti­on for antibiotic­s.

I think both parents and doctors need to be more thoughtful and not reach for what appears to be the easy fix. Doctors should take the time to talk to parents about why their children may not need antibiotic­s for many cases of sore throats, coughs and colds, and fevers.

For example, antibiotic­s should not be prescribed for a sore throat without a positive throat swab for “strep” (strep throat and a viral pharyngiti­s usually look pretty much the same to the naked eye). Instead, doctors and parents could create acontingen­cy plan to reassess the child at a certain point if they’re not recovering. Parents could also request a delayed antibiotic prescripti­on to be filled after a few days only if symptoms don’t improve.

To get these conversati­ons started, I encourage parents to ask these three important questions suggested by Choosing Wisely Canada, a national campaign to reduce unnecessar­y tests and treatments: 1. Does my child really need antibiotic­s? 2. What are the risks? 3. Are there simpler, safer options? Dr. Jeremy Friedman is a professor in the Faculty of Medicine’s Department of Paediatric­s and the associate paediatric­ian-in-chief at the Hospital for Sick Children (Sick Kids). Doctors’ Notes is a weekly column by members of the University of Toronto’s Faculty of Medicine.

 ?? DREAMSTIME ?? In many cases of fevers in kids, antibiotic­s are unhelpful, Dr. Jeremy Friedman says.
DREAMSTIME In many cases of fevers in kids, antibiotic­s are unhelpful, Dr. Jeremy Friedman says.

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