Toronto Star

TRUST YOUR GUT?

- Frank Campagna

Find out how your gut directly affects your quality of life.

What’s going on in your gut has a surprising­ly large effect on what goes on in your life.

Your microbiome is a complex ecosystem of microbes, including good and not-so-good bacteria, that live on and inside your body. The microbes that live in your gut are linked to overall health, digestive health, nutrition, cognition, mood, and your immune system. A balanced gut microbiome is one in which there are more good bacteria than the not-so-good variety. When the balance is tipped, the effect can extend further than you might think.

“The gut microbiome plays an important role in diet, in particular, digestion and fermentati­on of complex carbohydra­tes,” says Dr. Michael Surette of McMaster University and the Farncombe Family Digestive Health Research Institute. “Over 50 percent of your immune cells are in the gut and an important role of the microbiome is to maintain the immune system.”

Why is a balanced microbiome so important?

Your microbiome is shaped by many factors including diet, exercise, medication­s, stress, and genetics. However, the switch from having a well-balanced microbiome to having an unbalanced one can happen unexpected­ly, for many reasons. Digestive troubles are only the beginning when it comes to an unbalanced microbiome. The far-reaching effects can go from head to toe. “The gutbrain axis is a two-way communicat­ion between the brain and the gut which we now know is also influenced by gut bacteria,” says Dr. Surette.

The significan­ce of the two-way communicat­ion between the gut and the brain is an emerging area of microbiota science. Recent research has demonstrat­ed the influence of the microbiota on behaviour and mental health. Compounds produced by the gut microbiota serve as energy sources, signalling molecules, neurotrans­mitters, and precursors to neuroactiv­e compounds.

Genetics, birth method, early feeding practices, and medication­s received in the first year of life affect the initial establishm­ent of the gut microbiota. Later our diet, the environmen­t, and medication­s influence the diversity and abundance of organisms in the microbiota, which impact its function, influencin­g all the processes in which the microbiota plays a part to support overall wellness.

How can probiotics help?

A regimen of probiotic supplement­s can give you the power to impact the health of your microbiome by promoting a balanced level of good bacteria in your gut. “Probiotics can stimulate the immune system in a positive way, promoting balance or anti-inflammato­ry responses,” says Dr. Surette. “In some instances, they can also directly kill non-beneficial bacteria. Probiotics are transient and most pass through and do not colonize the gut, which is why you have to keep taking them.”

Choosing the right probiotic, however, can be difficult as what’s good for one person may not be effective in another. Still, some probiotics have been shown to be generally more effective than others. For instance, Lactobacil­lus rhamnosus GG is the number one clinically-studied probiotic strain in the world and has been shown to be effective in helping to manage and reduce the risk of antibiotic-associated diarrhea in both adults and children as well as promoting favourable gut flora for overall wellness benefits.

If you suspect your digestive tract to be unbalanced, there is very little reason not to try a probiotic supplement. “Probiotics are well regarded as safe for consumptio­n,” says Dr. Surette.

At the end of the day, what’s going on in your gut has a surprising­ly large effect on what goes on in your life. When you feel good, you can do good. By activating the power of the microbiome through probiotics, we can help everyone live their best life.

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 ?? Dr. Michael Surette Professor, McMaster University & Principal Investigat­or, Farncombe Family Digestive Health Research Institute ??
Dr. Michael Surette Professor, McMaster University & Principal Investigat­or, Farncombe Family Digestive Health Research Institute

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