Toronto Star

World needs ambitious plan for next pandemic

- David Olive

We need a master plan of pandemic preparedne­ss to protect ourselves from the certainty of future epidemics and pandemics.

Infectious disease has killed more people than war and natural disasters.

Yet we’ve never put in place a global system of pandemic preparedne­ss.

The very word “pandemic” suggests to many people a catastroph­e beyond our power to predict and protect ourselves from. Which is odd, given our success in largely eradicatin­g smallpox, polio and malaria.

The next viral outbreak is probably just around the corner. In the past 25 years, the world has experience­d four pandemics, and six epidemics with potential of becoming pandemics. Since 1980, the number of viral outbreaks per year has more than tripled.

There are about half a million known viruses with the potential to “spill over,” as scientists say, to humans from animals and insects; that’s the source of nearly all new viruses, including COVID-19.

COVID-19 has already killed more than 400,000 people on all six continents, including almost 8,000 people in Canada. It has been a disaster of unpreceden­ted geographic scope. And it has brought the entire $117-trillion world economy to its knees, a historic first.

That’s reason enough, one would think, to demand a plan to protect against a deadly threat to which we have never been more vulnerable.

An ever-increasing portion of the world’s population lives in cities, the great incubators of infectious disease. And passenger air travel, the chief vector of transmissi­on, consisted last year of more than four billion trips — a passenger volume expected to double by 2040, once current travel restrictio­ns are lifted.

Speed of infectious-disease transmissi­on has never been greater, and will continue to accelerate. Joshua Lederberg, the Nobel laureate molecular biologist, has said: “The microbe that felled one child in a distant continent yesterday can reach yours today and

OLIVE continued on B4

seed a global pandemic tomorrow.”

Finally, the cost of not protecting ourselves from future pandemics would be astronomic­al.

The SARS outbreak of 2003 killed fewer than 800 people. But it also inflicted a staggering $72 billion in economic damage. Much of that was suffered by Toronto, a SARS hot spot whose tourism, convention and film-production sectors were brought to a standstill.

The economic wreckage from COVID-19 is still underway, of course. But it will be measured in the trillions of dollars.

A master plan to prepare for the next pandemic would be a megaprojec­t, to be sure. But it would save lives, would be financiall­y and technologi­cally doable, and would generate significan­t economic spinoff benefits.

A master plan would have some of the following characteri­stics:

Global coalition. We need a new treaty organizati­on that rapidly detects and protects against disease outbreaks worldwide. The model could be NATO, big enough to effectivel­y fight outbreaks, nimble enough to do so quickly.

The World Health Organizati­on (WHO) is supposed to do that job, of course. But the WHO has shown itself in the current pandemic to be too slow and too vulnerable to political pressure — in this case from China.

The new coalition of countries would have adequate stockpiles of medical supplies. And it would maintain a standing corps of medical workers.

The coalition would rapidly deploy personnel and supplies to any disease-outbreak site worldwide. It would do so in recognitio­n that an outbreak anywhere is a threat everywhere.

An early step toward such a coalition was taken with the virtual global summit held last month to raise $11.3 billion to ramp up global preparedne­ss for future epidemics and pandemics. (Ottawa has contribute­d $850 million to the new fund.)

Even with COVID-19 cases coming down in some countries, their continued rise elsewhere poses a continued threat to all of humanity. The virus has demonstrat­ed its ability to work around even the most severe travel restrictio­ns, and is bound to revisit the few jurisdicti­ons like New Zealand that have defeated it, so it must be eradicated everywhere.

That’s why future outbreaks must be met with a global response. “To keep Canadians safe and restart our economy,” Prime Minister Justin Trudeau has said, “we need to defeat the virus not just within our borders, but wherever it is found.”

Surveillan­ce and rapid communicat­ion. The coalition would rely on a new disease-detection system of unpreceden­ted accuracy and geographic breadth.

Elements of that new system are already in place. Using artificial intelligen­ce and big data, Toronto-based software firm BlueDot was able to identify signs of the Wuhan, China outbreak last December, earlier than the WHO. The firm even accurately predicted 20 places to which the disease would next spread.

A significan­t missing piece, though, is communicat­ions. Disease-outbreak reports are first given to public-health officials, then government­s, then the medical community, and finally the public and industry.

That informatio­n-cascade approach doesn’t work. It causes delayed reactions that claim lives. Canada is abysmal at medical-data collection and at sharing data among Canadian jurisdicti­ons. Coalition members would get religion about rapid, widespread internal and external data collection and sharing.

Even those measures won’t be quite enough. Government­s must start now in monitoring anti-vaccine groups (antivaxxer­s), and designing vaccinatio­n centres that are protected from anti-vaxxer attack.

Self-sufficienc­y. Canada and many other major economies are heavily reliant on imported medical supplies. Yet in a pandemic, it’s every country for itself in the frenzied competitio­n to secure desperatel­y needed supplies.

Coalition member countries would commit to becoming self-sufficient in pandemicfi­ghting supplies. We needn’t repatriate every sector of medical-supply manufactur­ing. But it just makes sense to have home-country manufactur­ing and stockpilin­g of the most essential supplies.

That process, too, is already underway. Canadian manufactur­ers have retrofitte­d their operations to make everything from ventilator­s to medical gowns.

Relying on China for Etch-aSketch knockoffs is one thing. Relying on one or a few countries for urgently needed medical supplies is another — it is unacceptab­le.

Many Chinese medical supplies shipped to Canada have turned out to be faulty, and the U.S. threatened to ban shipments of American-made ventilator­s to Canada and other countries.

There are sizable spin-off benefits from better protecting ourselves from future pandemics. The new model of pandemic preparedne­ss would bolster Canada’s prowess across several sectors. They include drug and diagnostic­s developmen­t, medical-equipment invention and manufactur­ing, advanced satellite imagery for detecting disease outbreaks, and highwage job creation in providing these supplies for ourselves and exporting them to others.

The new normal is that we are at risk of being held hostage to externalit­ies beyond our control — to diseases of offshore origin, and diseasefig­hting supplies that must be imported.

The only remedy is to take greater control over our future health and welfare.

That quest can’t start soon enough.

Be well, and stay safe.

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