Toronto Star

Pioneering New Atopic Dermatitis Treatments Bring Hope and Relief

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Tania Amardeil

Atopic dermatitis is a chronic inflammato­ry skin condition characteri­zed by dry, itchy skin, with rashes that can be red, cracked, and even ooze and bleed. Flare-ups can be prompted by environmen­tal elements or “triggers” such as certain soaps, clothing fabrics, deodorants, carpet fibres, and dust. Overheatin­g, excessive sweating, low humidity, certain foods, and stress can also contribute to flare-ups.

Since our skin is outwardly visible to all with whom we interact, atopic dermatitis’ severe symptoms often have deep physical, emotional, and psychosoci­al impacts on patients — especially on adolescent­s. Sleep disturbanc­es, symptoms of anxiety and depression, and feelings of isolation are common amongst the estimated 17 percent of Canadians living with atopic dermatitis, as reported in the Canadian Skin Patient Alliance 2018 report

The Skin I’m In. Patients may also avoid physical or social activity and miss work or school as a result of their diagnosis.

A life-altering condition

“Living with eczema can be difficult. You stand out in front of all your classmates,” says Maryum, a teenager whosuffers from atopic dermatitis. “I was the only kid with different skin, and who had dry, itchy, inflamed skin.”

Atopic dermatitis affects people of all ages, but especially children and adolescent­s. “Atopic dermatitis is the most common form of eczema, and one out of every four or five children will be diagnosed with at least one symptom of atopic dermatitis,” explains Dr. Vipul Jain, an allergist and immunologi­st at Niagara Region Medical.

To date, treatments for atopic dermatitis have included various creams and lotions, topical steroid medication­s, and UV therapy. These treatments have had various measures of success in keeping the condition under control. “Steroids are just a temporary kind of thing,” says Saba, Maryum’s mother. “We tried UV light therapy for four or five months. It didn’t work. And then we were introduced to some newer options, new treatments in the market — the injectable­s.”

Promising news for adolescent­s with atopic dermatitis

Fortunatel­y for adolescent­s with atopic dermatitis, t here’s hope. Medical advancemen­ts — like the injectable­s that Saba mentions — are changing the way the condition is treated and managed. It’s now being viewed as an autoimmune disease rather than as a surface issue. This allows medical profession­als to treat the patient and not just the symptoms.

Finding effective treatment for adolescent­s suffering from the condition can be transforma­tive to their quality of life. “When you treat a patient’s atopic dermatitis, you help them feel what normal feels like. That’s a very powerful thing,” says Dr. Jain. “It’s an exciting time to be treating atopic dermatitis because of this newer, injectable therapy that’s available. It’s associated with potentiall­y less-serious side effects, the efficacy data is excellent, and patients do really well. Previously this treatment was only indicated in adult patients, but now it’s used to also treat adolescent patients.”

I'm hopeful about the future because there's been more awareness about eczema in recent yea and there have been innovation­s and medical advancemen­ts that will hopefully help people like me live a better life.

This is promising news for adolescent­s with atopic dermatitis. “I’m hopeful about the future because there’s been more awareness about eczema in recent years and there have been innovation­s and medical advancemen­ts that will hopefully help people like me live a better life,” says Maryum.

If you suffer from this condition, one of the new treatment options may be right for you. Talk to your dermatolog­ist, allergist, paediatric­ian, or general physician about finding the treatment that’s a perfect fit for you.

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