Toronto Star

Healthy lifestyle could lower Alzheimer’s risk, study says

Physical activity, alcohol consumptio­n, diet among factors that were studied

- KIERSTEN WILLIS

A newly published U.S. study shows there are lifestyle habits you can employ that could reduce the risk of Alzheimer’s.

Research of data published this month in the online issue of Neurology, the medical journal of the American Academy of Neurology, shows there was a substantia­lly lower risk of the progressiv­e disease in people who adhered to most or all of the specified healthy behaviours.

The findings were announced in a news release from the National Institutes of Health.

“This observatio­nal study provides more evidence on how a combinatio­n of modifiable behaviours may mitigate Alzheimer’s disease risk,” said Dr. Richard J. Hodes, the director of the National Institute on Aging. “The findings strengthen the associatio­n between healthy behaviours and lower risk, and add to the basis for controlled clinical trials to directly test the ability of interventi­ons to slow or prevent developmen­t of Alzheimer’s disease.”

In the study, researcher­s evaluated data from two institutef­unded longitudin­al study population­s: the Chicago Health and Aging Project (CHAP) and the Memory and Aging Project (MAP). Participan­ts with available data on their diet, lifestyle factors, genetics and clinical assessment­s for Alzheimer’s disease were selected.

Researcher­s scored participan­ts based on five healthy lifestyle factors: physical activity, not smoking, light-to-moderate alcohol consumptio­n, a highqualit­y diet and cognitive activities.

Then the team compared the scores with the results of Alzheimer’s diagnosis in the CHAP and MAP participan­ts. Compared to participan­ts with only one healthy lifestyle factor or none at all, the risk of Alzheimer’s was 37 per cent lower in those with two to three factors. People who adhered to four or all five factors were found to have had a 60 per cent lower Alzheimer’s risk.

“This population-based study helps paint the picture of how multiple factors are likely playing parts in Alzheimer’s disease risk,” said Dallas Anderson, program director in the Division of Neuroscien­ce at the National Institute on Aging. “It’s not a clear cause and effect result, but a strong finding because of the dual data sets and combinatio­n of modifiable lifestyle factors that appear to lead to risk reduction.”

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