Vancouver Sun

5 THINGS ABOUT THE (MALE) PILL.

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1 IT STOPS SPERM FROM SWIMMING

A breakthrou­gh scientific discovery that could be key to developing a male contracept­ive pill changes the way human cells work, switching off the ability of sperm to swim, rendering men temporaril­y infertile.

2 IT USES PEPTIDES

Peptides are short chains of amino acids. They occur naturally but can be created synthetica­lly. The breakthrou­gh came after scientists at England's Wolverhamp­ton University found some peptides could penetrate sperm cells. Then fertility experts at the University of Aveiro in Portugal, who identified the protein that drives sperm to swim, created a compound that turns the protein off.

3 IT WORKS FAST

Lead researcher professor John Howl of Wolverhamp­ton University said the new compound, made in the lab, showed immediate results. “When you take healthy sperm and add our compound, within a few minutes the sperm basically cannot move,” he said.

4 IT’S ONLY TEMPORARY

The discovery raises the prospect of a fast-acting pill or a nasal spray that a man could take hours or even minutes before sex. But researcher­s believe the effects of would wear off in a matter of days.

5 IT COULD CHANGE FAMILY PLANNING

Women are typically advised to stop taking birth-control pills weeks or even months before trying to conceive. The compound has been tested in the lab on bovine and human sperm, with live animal tests to start within three years.

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