Waterloo Region Record

Winfrey’s personal look at Henrietta Lacks

Plays role of daughter in new HBO documentar­y on cancer patient

- Andrea Mandell

Oprah Winfrey became obsessed with Henrietta Lacks’ story along with the rest of the world in 2010, but she never intended to star in HBO’s movie version, “The Immortal Life of Henrietta Lacks” (Saturday, 8 p.m.).

“For years, I was like, ‘I don’t want to do it. I don’t want to take this on. I just want to be a producer,’” says Winfrey, from her home in Montecito, Calif.

But she ended up taking a lead role as Lacks’ daughter Deborah, after optioning the rights to produce a film based on the 2010 bestseller. The book chronicles how the African-American Baltimore cancer patient died in 1951, not knowing her tumour cells were harvested by researcher­s at Johns Hopkins Hospital. Henrietta’s cells, known as HeLa, were later duplicated into “immortal” cell lines used by scientists for medical testing all over the world.

Author Rebecca Skloot’s nearly 400-page tome proved difficult to adapt. The non-fiction work weaves together the story of Lacks’ descendant­s, many of whom couldn’t afford health insurance despite their mother’s medical contributi­ons; HeLa’s effect on sprawling scientific breakthrou­ghs, from the polio vaccine to cancer research; and the ethical repercussi­ons of sampling body tissue without patients’ consent.

Early on, “there were some versions (of the script) where it was mostly science, and I was falling asleep,” says Winfrey. “We know, obviously, that getting people to digest science is a very difficult thing. Like, ‘Yes, you will enjoy spinach with a broccoli sauce.’ Being able to put it in a form where it is accessible and actually meaningful was the challenge.”

And hey, Skloot gets it. “It took me 11 years to turn it into a book,” says the author, who had to persuade the Lacks family to trust her after they’d been burned by others hoping to profit from their story. (The family remains divided on the HBO film.)

Winfrey’s tune changed when director George C. Wolfe (“Nights in Rodanthe”) signed on and rewrote the script to focus on Deborah and her quest to learn about what actually happened to her mother inside the then-segregated walls of Johns Hopkins.

“The biotech industry was born on the use of Henrietta Lacks’ cells,” says Wolfe. “HeLa is this incredible medical phenomenon. And then a few blocks away, there was a family that knew nothing about it.”

Rose Byrne (who “failed” biology and was a “miserable” science student) signed on to play Skloot, whose work “encompasse­s a lot of things: the line between science and ethics, race in America, the history of African-Americans,” she says. “It’s a perspectiv­e from a young white journalist and an older African-American woman. It’s a very unusual story.”

Renee Elise Goldsberry, just off a Tony-winning run in Broadway’s “Hamilton,” plays Henrietta in flashbacks. “I feel like I’m watching Oprah do this beautiful job of risking her sanity to uncover some potentiall­y painful informatio­n,” she says, noting how Deborah found the courage to open up to Skloot despite having “been so betrayed so many times.”

For Winfrey, the story brought back her early career. Despite spending eight years as a reporter in Baltimore, “I never once heard the name Henrietta Lacks. Or HeLa,” she says.

It’s why she’s put that Oprahsized stamp on the story.

“My inclinatio­n is to share informatio­n. That is a part of who I am,” says Winfrey. “I find a thing; I like it, (I share it): whether it is a new English muffin which I discovered last year in Napa or it’s my favourite panini maker. It’s the same thing with a story, a book, an article of clothing, a lipstick — whatever, ‘You gotta know about this thing!’ So I was excited for as many people to know about Henrietta Lacks as I could reach.”

 ?? QUANTRELL COLBERT, HBO ?? Oprah Winfrey in HBO’s “The Immortal Life of Henrietta Lacks.”
QUANTRELL COLBERT, HBO Oprah Winfrey in HBO’s “The Immortal Life of Henrietta Lacks.”

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