Study on Identification of Principal Medicines in Prescriptions in Fu Xing Jue in Dunhuang Based on Prescription Metrology

LI Tingbao, YANG Pengfei

LI Tingbao, YANG Pengfei

Key Laboratory of Dunhuang Medical Ministry of Education, Gansu University of Chinese Medicine,

Lanzhou 730000, China

Abstract: Objective To analyze the principal medicines in prescriptions in Fu Xing Jue in Dunhuang based on prescription metrology; To clarify the compatibility ideas of prescriptions; To provide references for the clinical application. Methods Prescriptions in Fu Xing Jue recorded in Dun Huang Shi Ku Mi Fang Yu Zhen Jiu Tu were selected. Prescription metrology was used to calculate the effective relative dosage, identify the principal medicines in prescriptions, and calculate the indexes of principal medicines. Characteristics of taste and belonging meridians, and the degree of conformity between identified principal medicine and identified principal medicine by ancient doctors were analyzed. Results Totally 61 prescriptions were included, covering 64 kinds of Chinese materia medica, among which 57 prescriptions were with 1 kind of principal medicines and 4 prescriptions were with two kinds of principal medicines. 26 kinds of principal medicines were obtained after removing repetition. The principal medicines with the biggest index were was Aconiti Lateralis Radix Praeparaia, followed by Gardeniae Fructus, Coptidis Rhizoma, Gypsum Fibrosum, and Pinelliae Rhizoma. The rate of coincidence between identified principal medicines and the established principal medicines in the literature was 83.87%. Compared with the characteristics of non-principal medicines, the characteristics of principal medicines were cold and bitter, and more principal medicines belonged to gallbladder, bladder, kidney meridians. Principal medicines were fewer warm and sweet, and belonged to lung, kidney, spleen and liver meridians than non-principal medicines. Conclusion The analysis on the compatibility of principle medicines showed that prescriptions in Fu Xing Jue in Dunhuang mainly treat cold and heat epidemics. This study can identify principal medicines with high accuracy, which can provide references for research on prescriptions in Fu Xing Jue in Dunhuang.

Keywords: prescriptions in Dunhuang; Fu Xing Jue; prescription metrology; identification of principal medicines; literature research