Global Times

Race with time

- By Hu Yuwei

Sinovac Beijing vaccine production facility works overtime to supply global inoculatio­n

The Global Times reporters on Sunday visited the COVID- 19 vaccine Beijing manufactur­ing plant of leading Chinese vaccine producer Sinovac to see how vaccines go through a complex packaging process - from vaccine bulk grouting to packaging – before they are shipped to vaccinatio­n sites around the world.

The vaccine production follows a strict and profession­al protocol. First, the Vero cells of the coronaviru­s will be transferre­d to a bacterial jar through a fullyseale­d pipe so the virus can multiply in the jar. There will then be a transfer to a tailored medical jar for virus inactivati­on lasting two or three days. Those two steps will be carried out in the bio- safety level P3 bio- pharmaceut­ical production workshop.

After various tests, the vaccine pulp developed from the inactivate­d virus will be delivered to the production line for packaging with a sterile bottle and rubber plug. Before packaging, each vaccine is labeled and a batch number is tagged to trace the producer and status of transit.

The entire production line involves hundreds of testing items, covering key indicators of safety and effectiven­ess, the Global Times learnt from Sinovac.

The vaccine is stored in cold storage at a temperatur­e of two to eight degrees Celsius. But thermal stability tests have shown the vaccine can be effective for injection within 42 days at 25 degrees and 21 days at 37 degrees.

For partner countries with independen­t vaccine packaging capabiliti­es, Sinovac usually offers the vaccine bulk to the other countries such as Brazil and Indonesia upon mutual agreement.

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 ??  ?? ▴ The production chain uses digital technology to strictly monitor every step of production and packaging.
▶ A staff member shows finished vaccines filled in the vial.
▴ The production chain uses digital technology to strictly monitor every step of production and packaging. ▶ A staff member shows finished vaccines filled in the vial.
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 ??  ?? ◀ Staff inspect the sterile needles and syringe bottles for the COVID- 19 vaccine.
◀ Staff inspect the sterile needles and syringe bottles for the COVID- 19 vaccine.
 ?? Photos: Li Hao/ GT ?? ▾ Vaccines are stored in a refrigerat­ed warehouse before being shipped out.
Photos: Li Hao/ GT ▾ Vaccines are stored in a refrigerat­ed warehouse before being shipped out.
 ??  ?? ▴ Staff members seal the vaccines into plastic packaging.
▴ Staff members seal the vaccines into plastic packaging.
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