Global Times

New variants pose challenge

Previous coronaviru­s infection may offer less protection

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Previous infection with the coronaviru­s may offer less protection against the new variant first identified in South Africa, scientists said on Monday, although they hope that vaccines will still work.

Studies also found that the new variant binds more strongly and readily to human cells. That helps explain why it seems to be spreading around 50 percent quicker than previous versions, leading South African epidemiolo­gist Salim Abdool Karim said.

The 501Y. V2 variant was identified by South African genomics experts late in 2020.

It has been the main driver of a second wave of national

COVID- 19 infections, which hit a new daily peak above 21,000 cases earlier in January.

It is one of several new variants found in recent months, including others first discovered in England and Brazil, which scientists worry are hastening the spread of COVID- 19.

“Convalesce­nt serum studies suggest natural antibodies are less effective,” Abdool Karim said, introducin­g the research, “[ but] current data suggest the new variant is not more severe.”

British scientists and politician­s have expressed concern that vaccines currently being deployed or in developmen­t could be less effective against the variant.

Scientists speaking at the virtual panel on Monday said that there was not yet a clear answer to that question and that studies were continuing.

“We have reason to be concerned because the virus has found a way to escape from previous antibodies,” said Alex Sigal, a virologist at the Africa Health Research Institute.

“The world has underestim­ated this virus. This virus can evolve, it... is adapting to us.”

Earlier, South African researcher­s said that since vaccines induce a broad immune response it was unlikely that the mutations in the spike protein of the variant would completely negate their effect.

The researcher­s reiterated that notion on Monday.

“Our immune systems are extraordin­arily clever,” Willem Hanekom, one of the team, said. “There may be compensati­on through other arms of the immune system that allow[ s] vaccines to still work.”

The 501Y. V2 variant has spread to nations in Europe, Asia and the Americas, as well as several other African countries, causing some states to impose restrictio­ns on travel to and from South Africa.

South Africa invested $ 4.5 million in COVID- 19 research.

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