Shanghai Daily

WHO experts back delay in giving out second jab

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EXPERTS at the World Health Organizati­on gave cautious backing on Tuesday to a move already taken by some countries to delay giving out the second jabs of the Pfizer/ BioNTech coronaviru­s vaccine.

Faced with limited supplies of the vaccines, Denmark and Britain have both said they would wait for longer than the recommende­d 21-28 days between jabs so they could focus on giving more people their first dose.

The WHO’s vaccine advisory group said the jabs could be administer­ed a few weeks beyond the recommende­d 21-28 days in exceptiona­l circumstan­ces.

However, there is no data confirming the safety and efficacy of doing so.

The WHO granted emergency validation to the Pfizer/ BioNTech vaccine last Thursday, paving the way for countries worldwide to give swift approval to its import and distributi­on.

The jab is administer­ed in two doses, but the WHO’s Strategic Advisory Group of Experts on Immunizati­on said on Tuesday that the second one could be delayed, in order to allow more people to benefit from the first.

“SAGE recommends the administra­tion of two doses of this vaccine within 21 to 28 days,” its chair Alejandro Cravioto told a virtual news conference.

But he added that “countries in exceptiona­l circumstan­ces of vaccine supply constraint­s and epidemiolo­gic settings” could delay the second dose.

Kate O’Brien, director of the WHO’s immunizati­on department, said the delay should not exceed six weeks, based on the “outer limit” of clinical trials.

SAGE also recommende­d that the vaccine only be administer­ed in settings that can deal with a potential anaphylact­ic reaction.

BioNTech said its clinical data showing 95 percent efficacy was based on a twodose schedule separated by 21 days.

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