Stabroek News

Artificial leaf copies nature to manufactur­e medicine

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(Reuters) - Dutch scientists have developed an artificial leaf that can act as a mini-factory for producing drugs, an advance that could allow medicines to be produced anywhere there is sunlight.

The work taps into the ability of plants to use sunlight to feed themselves through photosynth­esis, something industrial chemists have struggled to replicate because sunshine usually generates too little energy to fuel chemical reactions.

The leaf-inspired micro factory mimics nature’s efficiency at harvesting solar radiation by using new materials called luminescen­t solar concentrat­ors with very thin channels through which liquid is pumped, exposing molecules to sunlight.

“Theoretica­lly, you could use this device to make drug compounds with solar energy anywhere you want,” said lead researcher Timothy Noel at Eindhoven University of Technology.

By doing away with the need for a power grid, it may be possible one day to make malaria drugs in the jungle or even medicines on Mars in some future space colony, he believes.

The device, made from silicone rubber, can operate even when there is diffuse light, which means it will work under cloudy skies. However, there is still a way to go to scale up the process to make it commercial­ly viable.

Noel and his colleagues, who published their research in the science journal Angewandte Chemie on Wednesday, are now trying to improve energy efficiency further and increase output.

Because the artificial leaf relies on micro-channels to bring chemicals into direct contact with sunlight, each unit needs to be small - but they could be easily linked together to increase production.

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