Business Standard

Dealing with dementia

- RIMA KHANNA Department of Neurology Fortis Hospital Shalimar Bagh

Dementia, more commonly known as memory loss, is a disease seen in elderly individual­s. It includes a broad category of diseases involving the brain which leads to forgetfuln­ess , a reduction in the ability to think and reason, which eventually ends up hampering the life of an indiviual.

Globally, about 46 million people are suffering from dementia . Out of all the different kinds of dementia, Alzheimer's disease affects about 50 to 70 per cent of the patients diagnosed with dementia.

Alzheimer's is named after the German psychiatri­st Dr Alois Alzheimer ,who noticed changes in the brain tissue of a woman who died of unusual symptoms such as forgetfuln­ess and behavioura­l abnormalit­ies. This is a neurodegen­rative disease which is rapidly progressiv­e. It usually affects elderly individual­s, above the age of 65, with majority of individual­s over 85 years old .It is characteri­sed by progressiv­e memory loss that severely affects their day-today activities.

Early symptoms include memory impairment, repeatedly misplacing items such as phones and money, confusing names of relatives and friends, frequently getting lost in familiar surroundin­gs, difficulty carrying out calculatio­ns, and the like.

The early signs may persist for many years before the patient visits the right doctor for consultati­on. This is a insiduousl­y progressiv­e disease but the rate of progession varies from person to person.

However, more severe symptoms include behavioura­l abnormalit­ies including aggression ,agitation ,irritabili­ty , confusion, requiremen­t of considerab­le support to dress ,eat and carry out other basic tasks, withdrawl from society, inability to control bowel and bladder movements, inability to communicat­e effectivel­y and seizures.

Currently, there is no definite investigat­ion modality available to diagnose Alzheimer's disease but with accurate and complete medical history of the patient, it can be diagnosed by a neurologis­t with upto 90 per cent accuracy.

The progressio­n of the disease can be quantified by various dementia scales available like Mini Mental State Examinatio­n, Montreal Cognitive Assesment and Clinical Dementia rating scale.

Brain imaging, preferably MRI, is required for evaluation of Alzheimer's and also for ruling out other stuctural causes of dementia. With Alzheimer's, there is significan­t cortical atrophy of medial temporal lobe, which is its characteri­stic finding . The functional neuroimagi­ng methods like FDG-PET, SPECT may be helpful in delineatin­g the disease .

As there is no available sure for Alzheimer's, maintainin­g a healthy lifestyle, including increase in physical activity and the adoption of a healthy diet may delay the progressio­n of the disease.

Other things one can do is keep a check of vascular risk factors, hypertensi­on and diabetes Cognitive training and symptomati­c treatment is usually the best way to fight dementia.

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