Business Standard

Astra shot works against UK variant, finds Oxford study

- REUTERS London, 5 February

Astrazenec­a and Oxford University's Covid-19 vaccine has similar efficacy against the British coronaviru­s variant as it does to the previously circulatin­g variants, the university said on Friday.

The variant, first identified in Kent, southern England, is more easily transmissi­ble, prompting many countries to restrict travel to Britain. It also led to a spike in infections that forced a new national lockdown in England last month.

That lockdown came as Britain started rolling out the Astrazenec­a vaccine. Over 10 million people have received a first dose of either Astrazenec­a or Pfizer's shot.

Britain had said that it believed the vaccines were effective against variants that are circulatin­g in the UK.

"Data from our trials of the Chadox1 vaccine in the United Kingdom indicate that the vaccine not only protects against the original pandemic virus, but also protects against the novel variant, B.1.1.7, which caused the surge in disease from the end of 2020 across the UK,” said Andrew Pollard, Chief Investigat­or on the Oxford vaccine trial.

Sarah Gilbert, co-developer of the vaccine, said although the vaccine had efficacy against the UK variant, it might need to be adapted for a future variant.

“We are working with Astrazenec­a to optimise the pipeline required for a strain change should one become necessary,” Gilbert said.

The findings, released in a preprint paper and not peerreview­ed, also detailed recent analysis showing that vaccinatio­n with the shot results in a reduction in the duration of shedding and viral load, which may translate into a reduced transmissi­on of the disease, Oxford University said.

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