Gene Editing: Terrible Turning Point?

But the possibilities are very real, and very close.

Meanwhile, the first experiments in gene editing the cells of a living human are already taking place, in China. That could lead to a medical breakthrough in gene therapy, or it could point the way to inheritable interventions.

We are also at a critical point in the rapid development of “gene drive” technology. With this, modified genes spread rapidly to take over entire populations of a species. The technology could even lead to weapons of mass destruction, according to James Clapper, the U.S. director of national intelligence. So far, calls for a moratorium have been rebuffed.

In the U.S., important scientists have been discussing what they call “HGP–Write”: a long-term effort to synthesize a complete human genome from scratch. That could lead to interesting science, but some of those involved are promoting far-fetched concepts such as “virus-free people”. Some also support making “more intelligent people” and applying other so-called “enhancements”.

Should we be worried? Yes, we certainly should, especially given the attitudes of the newly-elected President of the United States. Mr. Trump calls himself a “gene believer” who is “proud to have that German blood. There’s no question about it. Great stuff.”

This is the language of eugenics, as originally defined in 19th-century England, codified into law in California and other U.S. states, and brought to its ugliest culmination so far in Nazi Germany.

Will we get to that point? Let’s hope not.

Opinion polls clearly show that significant majorities are more worried than enthusiastic about attempts at human enhancement for any reason, even including reducing risk of disease. Some 45 countries have already written laws prohibiting the use of genetic procedures to change the traits we hand down to future generations. Will the U.S., China and others join them?

The next year could be critical. We can choose — as a species — to reject the idea of remaking people and our environment. Or we can sit back and do nothing, and watch what happens. It is a scary time.

Meanwhile, the UK’s fertility regulator has given the green light to a treatment that will make it possible for babies to be made from two women and a man. The new advancement in in-vitro fertilisation has been developed by doctors in Newcastle. The first child to be born in the UK through the new method could arrive by the end of 2017. The writer is a regular contributor to Biopolitical Times, the blog of the Center for Genetics and Society.