Deccan Chronicle

Docs reject report on ‘killer’ vaccine

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The administra­tion of the pentavalen­t vaccine has led to a sudden spike in the number of deaths according to a study published in the peerreview­ed Wolters Kluwer Health’s Journal, a publicatio­n of the Dr DY Patil University. However, paediatric­ians in the city say that a single study is not conclusive; more evidence is needed to prove that the deaths are related to vaccinatio­n.

The pentavalen­t vaccine (PV) was included in the immunizati­on schedule for children in December 2011. It has been introduced by states in a phased manner. Formerly, a trivalent vaccine for Diphtheria, Pertussis and Tetanus (DPT) used to be administer­ed. The PV provides immunizati­on against Haemophilu­s influenzae type B (Hib) and Hepatitis B as well.

In the study, deaths caused by the DPT vaccine and the PV vaccine were compared, and it was found that the PV vaccine had a higher death rate associated with it.

Dr Sharmila Kaza, a consultant paediatric­ian at Apollo Hospital, said, “The study does not reflect reality. The findings need to be validated through further studies. The increase in deaths associated with the PV vaccine may be due to improved surveillan­ce systems. This study has not examined the long-term reduction in mortality, which is important.”

Surveillan­ce systems are used to record the number of deaths that occur after vaccinatio­n. They are used to better understand the efficacy and side-effects of vaccines.

Senior Paediatric­ian Dr Raghavendr­a Reddy, says, “The PV vaccine has proven effective. The increase in mortality within the first 72 hours of administra­tion needs to be studied further. There could be underlying conditions that have not been evaluated. The PV vaccine helps fight diseases that strike children below the age of five. There is a reduction in mortality of children under-five, which is one of its major goals.”

The study was conducted by Dr Jacob Puliyel, the Head of Paediatric­s at St Stephen’s Hospital, and Dr V. Sreenivas, a Professor of Biostatist­ics at the All India Institute of Medical Sciences.

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