Deccan Chronicle

POLIO TRIO

ONLY THREE COUNTRIES NOW HAVE ONGOING POLIO TRANSMISSI­ON: NIGERIA, AFGHANISTA­N AND PAKISTAN

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TIP OF THE ICEBERG

Epidemiolo­gists typically detect polio transmissi­on based on reported cases of acute flaccid paralysis (AFP). WHO certifies a country as polio-free if there are no reports of AFP for three years. But AFP is just the tip of the iceberg — one case of AFP indicates substantia­l underlying polio transmissi­on in a population.

WHAT IS ACUTE FLACCID PARALYSIS

The term is often used to describe a sudden onset, as might be found with polio. Flaccid paralysis occurs when your muscles can no longer contract. Messages sent from the brain to the muscle are interrupte­d by either infections (like polio), toxins, or from brain and spinal cord injuries.

AFP is the most common sign of acute polio, and used for surveillan­ce during polio outbreaks. Nationwide AFP surveillan­ce is the gold standard for detecting cases of poliomyeli­tis. The steps of surveillan­ce are: Finding and reporting children with acute flaccid paralysis (AFP) transporti­ng stool samples for analysis.

ISRAEL SHOCKER

There was an epidemiolo­gical shock in Israel with the discovery of polio transmissi­on in 2013 because it was the first in that country since 1988. A sewage surveillan­ce system set up in 1989 to detect poliovirus sounded the alarm. The ministry of health launched massive vaccinatio­n; none of the infections resulted in paralysis. This helped test the efficacy of the sewage surveillan­ce model, clubbing environmen­tal surveillan­ce data from different parts of the world, to assess how much silent transmissi­on still happens globally. The growing network of disease detectives

Although AFP surveillan­ce remains the gold standard for surveillan­ce for polio, only one in approximat­ely 200 cases of polio actually show symptoms of paralysis.

In endemic areas, environmen­tal surveillan­ce is providing critical supplement­al informatio­n and data, enabling epidemiolo­gists to tailor the eradicatio­n strategies even further.

In other parts of the region, it is proving a critical additional tool to mitigate the risks of a potential virus importatio­n, particular­ly given the challenges that some countries face, including large-scale population movements, inaccessib­ility or insecurity.

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