Deccan Chronicle

Covid vaccine: 5k sign LOCKDOWN TAKEN OFF FROM VIRUS EPICENTRE WUHAN

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Beijing, March 25: Around 5,000 people have signed up for the phase I clinical trial of recombinan­t novel Covid-19 vaccine in Chinese city Wuhan where the virus first emerged late last year.

The recruitmen­t for participan­ts ended this week with nearly 5,000 volunteers signing up for the trial, state-run Beijing News reported on Wednesday. A single-centre, open and dose-escalation phase I clinical trial for recombinan­t novel Covid-19 vaccine (adenoviral vector) will be tested in healthy adults aged between 18 and 60 years, according to the ChiCTR (China Clinical Trial Register).

The trial, led by experts from the Academy of Military Medical Sciences, gained its approval on March 16 and the research is expected to last half a year. Requiring at least 108 participan­ts, the trial will be conducted in Wuhan, capital of Hubei province, the region worst-affected by the virus in the country, state-run China Daily reported.

Participan­ts will experience 14-day quarantine restrictio­ns after being vaccinated and their health condition will be recorded every day. Chinese scientists are hastening the developmen­t of Covid-19 vaccines through five approaches — inactivate­d vaccines, genetic engineerin­g subunit vaccines, adenovirus vector vaccines, nucleic acid vaccines and vaccines using attenuated influenza virus as vectors.

So far, most teams are expected to complete preclinica­l research in April and some are moving forward faster, Wang Junzhi, an academicia­n with the Chinese Academy of Engineerin­g said. Wang noted that research and developmen­t of Covid-19 vaccines in China is not slower than foreign counterpar­ts and has been carried out in a scientific, standardis­ed and orderly way.

China has stepped up the process to finalise vaccines to counter Covid-19 after Kaiser Permanente research facility in Seattle and Washington stole the march and began human trials. China reported no new domestic cases on

Beijing, March 25: China on Wednesday downgraded the risk level of the Covid-19 in its epicentre Wuhan from high to medium and resumed bus services within the city for the first time since the nineweek lockdown even as a new study said thousands of positive cases there may have gone under the radar. China has decided to lift the three-month lockdown on more than 56 million people in Hubei province. However, the lockdown of Hubei's capital Wuhan will end on April 8.

Wednesday. But there were another 47 imported infections from overseas, the National Health Commission said. In total, 474 imported infections have been diagnosed in China -mostly Chinese nationals returning home.

 ?? — AP/PTI ?? An man is treated in a hospital after a gunman stormed a religious gathering of Afghanista­n’s minority Sikhs at a gurdwara in Kabul on Wednesday.
— AP/PTI An man is treated in a hospital after a gunman stormed a religious gathering of Afghanista­n’s minority Sikhs at a gurdwara in Kabul on Wednesday.

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