Deccan Chronicle

CCMB spots more infectious Covid strain in India

Similarity in viral genome positive as vaccine will be effective worldwide

- BALU PULIPAKA I DC

A more infectious strain of

SARS-CoV-2, the Coronaviru­s that causes Covid

19, is now being increasing­ly seen in India, scientists at the Centre for Cellular and Molecular Biology (CCMB) have said.

Currently, 70 per cent of all Indian and global SARS

CoV2 virus variants fall into this category of the more infectious variety, according to the scientists.

Dr Rakesh K. Mishra, CCMB director, made it clear that despite its more infectious nature, there is no evidence that this muta

● THERE IS no proof that this mutation — A2a clade — is more difficult to deal with clinically.

tion — A2a clade — is more difficult to deal with clinically.

“As expected for a strain which is more infectious, the A2a clade quickly became dominant in India just like everywhere else.”

The similarity in the viral genome globally should be considered positive news, because a vaccine or a drug targeting this mutation will work with the same effectiven­ess all over the world, Dr Mishra, a co-author of CCMB’s latest study on the virus, said.

He made it clear that no clade of the virus at present has been conclusive­ly shown to be associated with a more severe form of

Covid-19, or cause an increased risk of death.

The increasing prevalence of the more infectious strain comes as CCMB scientists continued with their study in June that found the I/A3i clade of the virus was a distinct

Covid-19 causing variant among Indians.

That study, that resulted from an analysis of more than 2,000 SARS-CoV2 genomes from India available in the public domain, found that the particular clade was recognised by the presence of four specific variations in their genomes. At that time, 41 per cent of all Indian

SARS-CoV-2 genomes belonged to this clade.

The current analysis showed that the proportion of the A3i clade dropped to

18 per cent, which was predicted by the CCMB study as this variation was expected to be bad for the virus. “This is exactly what we see now,” Dr Divya Tej Sowpati, a CCMB scientist who is leading the study, said.

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