Liquor linked to mus­cle fa­tigue

Down to Earth - - SCIENCE & TECHNOLOGY -

Mus­cle fa­tigue is a com­mon symp­tom as­so­ci­ated with reg­u­lar al­co­hol con­sump­tion. This hap­pens be­cause al­co­hol re­duces Mfn1, a protein, by as much as 50 per cent in the body. Mfn1 helps in mi­to­chon­dria fu­sion, a process nec­es­sary for re­pair­ing dam­aged mi­to­chon­dria. As mi­to­chon­dria are the cell or­ganelle re­spon­si­ble for pro­duc­ing en­ergy, the fall in Mfn1 and in mi­to­chon­dria fu­sion cause mus­cle fa­tigue. TheJour­nalofCel­lBi­ol­ogy,April21(on­line)

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