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Liquor linked to muscle fatigue

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Muscle fatigue is a common symptom associated with regular alcohol consumptio­n. This happens because alcohol reduces Mfn1, a protein, by as much as 50 per cent in the body. Mfn1 helps in mitochondr­ia fusion, a process necessary for repairing damaged mitochondr­ia. As mitochondr­ia are the cell organelle responsibl­e for producing energy, the fall in Mfn1 and in mitochondr­ia fusion cause muscle fatigue. TheJournal­ofCellBiol­ogy,April21(online)

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