Down to Earth

Environmen­t trumps heredity

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ENVIRONMEN­TAL FAC TOR S have a greater impact on an individual's immune system than hereditary factors. This has emerged from a study on 78 pairs of identical twins (almost 100 per cent geneticall­y identical) and 27 pairs of fraternal twins (50 per cent geneticall­y identical). Analyses of blood samples of these twins for 200 immune-system components found that environmen­tal factors, such as exposure to toxins and vaccinatio­n, had a greater impact than heredity on about two-thirds of the components. Cell, January 15

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