Down to Earth

Beyond DNA

Maurizio Meloni's book is a fascinatin­g social and political history of human heredity spanning over 150 years RAKESH KALSHIAN

- The gene story

A new book gives an account of the politics of human heredity during the past 150 years

POLITICAL BIOLOGY: SCIENCE AND SOCIAL VALUES IN HUMAN HEREDITY FROM EUGENICS TO EPIGENETIC­S Maurizio Meloni, Palgrave Macmillan | £25.00 | 284 pages

RECENTLY, THE Union Ministry of Ayurveda, Unani, Siddha and Homeopathy (ayush) issued a booklet that advised pregnant women to “detach themselves from desire, anger, attachment, hatred and lust,” as well as “shun non-vegetarian food to deliver a healthy baby”. It immediatel­y sparked off a kerfuffle in the media as suitably peeved progressiv­es slammed it as yet another attempt by the Hindu right at insinuatin­g antiquated, sexist, and unscientif­ic ideas into the body politic.

That said, while there is good reason to be cautious about the rise of right-wing orthodoxy in recent times, the idea that a person’s life history—her physical and emotional experience, her dietary habits, her social milieus—may leave a lasting impression on her as well as on her descendant­s is passé no more. Epigenetic­s, as this new emerging science is called, tries to make sense of traits and phenomena, such as persistent­ly skinny babies in a population, or the recurrence of a disease, that cannot be explained by dna alone: there is something else going on beyond the dna’s

ken that’s making it behave out of line. Hence, if scientists can seriously entertain the possibilit­y that the disproport­ionate number of underweigh­t babies born to African-American women might have something to do with their slave past, to dismiss the idea that certain actions of a pregnant mother might affect her baby as pure nonsense may seem a little cavalier.

This subtext of epigenetic­s is the immediate provocatio­n behind Maurizio Meloni’s Political Biology: Science and Social Values in Human Heredity from Eugenics to Epigenetic­s, a fascinatin­g social and political history of human heredity spanning over 150 years from Darwin to the present moment. Eschewing the whiggish illusion of history as a collection of linear events that move inevitably towards progress, he uses concepts such as dispersion, epistemic break, switch and caesuras to weave an intricate narrative in which the script, in this case ideas and statements about human heredity, unfolds in surprising and unforeseen ways under changing social and political circumstan­ces.

Meloni, who teaches social theory at the University of Sheffield in the United Kingdom, begins his story around the publicatio­n of Darwin’s Origin of Species. This is a time when Darwin’s theory of evolution by natural selection is up against Lamarck’s ideas about inheritanc­e of acquired traits. It’s true that most of us have a linear and highly abridged sense of history, which often makes us assume that intimately connected ideas, such as evolution and genes, would have arisen in some predetermi­ned logical progressio­n. But, as Meloni enlightens us, truth, more often than not, is elliptical. Darwin, for instance, believed even traits changed by conditions of life were passed on, even as, unbeknowns­t to the larger scientific community, a German friar called Gregor Mendel was laying out the laws of heredity with his pea plant experiment­s. Meloni argues that Mendel’s fellow scientists, indeed Mendel himself, could not appreciate the significan­ce of his results as no one before 1900 could divorce nature from nurture in their minds.

However, not knowing the nitty-gritty of heredity didn’t deter scientists from pontificat­ing on it. Meloni recounts how in the last decades of the 19th century three scientists, notably Francis Galton, August Weismann (introduced the idea of germplasm) and Wilhelm Johannsen (he coined the words kgenotypey, kphenotype­y and kgeney), engineered a decisive shift from soft heredity (nature plus nature) to hard heredity (only nature). This sundering of heredity from environmen­t was captured by a catchy metaphor: the seed of nature always prevails over the soil of nurture.

Galton, who was trained as a statistici­an, believed that scientists should actively influence public policy along scientific lines for society’s larger good. As part of his political rhetoric, Meloni writes, “he attacked rank privilege in the name of talent.” Little wonder, Galton is known as the father of eugenics, as his case for a meritocrat­ic society sat well with his championin­g of hard heredity.

The stage was set for eugenics to spread its wings. Meloni next takes us on remarkable journey into the wild adventures in the eugenics movement from 1900 to 1945. Positive eugenics entailed improving human race by preferenti­al perpetuati­on of the fittest. But the definition of the fittest depended on the eugenicist’s political ideology, ranging from a successful capitalist to a successful revolution­ary.

However, the trouble with positive eugenics was that technologi­es needed to carry out the project, such as ivf or sperm banks, were still a thing of the future. Hence, most nations in the west carried out horrendous experiment­s in the name of negative eugenics—forced sterilisat­ion, denial of citizenshi­p based on IQ tests, hormonal treatment of homosexual­s, and, under the Nazis, the infamous Aktion T4 euthanasia program in which over 70,000 sick and mentally-ill Germans, not just Jews, were gassed or injected with poison.

Interestin­gly, the bug of eugenics infected minds across the political spectrum. Meloni describes in engrossing detail how the cat’s cradle between political ideology and hard heredity produced all manner of eugenicist­s, from left Lamarckian­s (make living conditions better), to right Lamarckian­s (weed out the sick, stupid, insane and degenerate), to left Mendelians (propagatin­g germplasm suited to socialism), and right Mendalians (improving race using quality germplasm).

For Meloni, the early 20th century history of the politics of heredity “clearly demonstrat­es that biological doctrines do no entail political values. He asks provocativ­ely: “Had Stalin made (geneticist Herman) Muller, not Lysenko, his official biologist, would we think today of nurture and soft heredity as liberal values?”

Meloni’s next stop is the post-war period 1945-2000 when the modern synthesis of Darwinian evolution and Mendelian genetics is enshrined in the form of the central dogma of molecular biology—that genetic arrow moves in only one direction: dna-rna-Protein. Again, Meloni argues that post war, “the politics of biology abandoned the bold social engineerin­g spirit of interwar eugenics and reposition­ed itself successful­ly within the liberal-democratic framework.” He believes the revised contract is robust having survived the return of eugenics in the garb of sociobiolo­gy and evolutiona­ry biology.

However, Meloni is curious about the political ramificati­ons of epigenetic­s and the return of soft heredity. Even as he discerns in epigenetic­s, a liberating potential against sexism or racism, he advises against complacenc­y: “Today, as throughout history, scientific theories do not decide political values.” In the light of the rise of reactionar­y forces in South Asia, the ayush advisory, however innocuous, warrants a more alert skepticism on the part of citizens.

Meloni’s writing style may seem a little dense to some, especially to the lay reader, as it is written for scholars. While it is certainly essential reading for students of history and politics of science, I would urge anyone who feels overwhelme­d by the pervasiven­ess of modern biology and its medical imprint, and who wish to make sense of it, to at least give it a cursory read.

Meloni argues that post1945, the politics of biology has abandoned the bold social engineerin­g spirit of interwar eugenics and reposition­ed itself within the democratic framework

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TARIQUE AZIZ / CSE

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