Hindustan Times (Bathinda)

HUMAN TRIALS

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PHASE 1: This is a stage of research that focuses on the safety of a drug. It’s conducted with healthy volunteers, and goal is simply to determine the drug's most frequent and serious side effects. This usually involve a small number of participan­ts PHASE 2: This is the first of the phases to test efficacy. This process begins usually with health volunteers between 18 and 50. The process is often split further depending on how large the trial groups become

PHASE 3: This is the most crucial phase of the trials, where large groups are used. These trials involve doubleblin­ding and randomisat­ion throughout the large groups in which some will be given the vaccine and some placebos. The objective is to determine enough data that will establish efficacy and rule out external factors

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