Hindustan Times (Chandigarh)

Cansino candidate shows promise

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NEW DELHI: A Covid-19 vaccine developed by Cansino Biologics Inc and China’s military research unit has shown to be safe and induced immune response in most of the recipients, researcher­s said on Monday.

The Cansino candidate, named AD5-NCOV, is one of a handful of vaccines that have shown some promise in human testing and are gearing up for late-stage trials, along with projects involving Moderna Inc, Biontech SE and Inovio Pharmaceut­icals Inc.

While Cansino’s vaccine has yet to start late-stage large-scale clinical trials to assess how well it works to prevent people from becoming infected, it has received the green light to be used in China’s military.

The results from the mid-stage study, published in the medical journal Lancet, supports the testing of the vaccine candidate in a large trial, the study authors said.

The vaccine candidate uses a virus called adenovirus to carry genetic material from the new coronaviru­s’ protein into the human body, a method also used by researcher­s at the University of Oxford and Astrazenec­a for their vaccine candidate.

The immune responses elicited by the vaccine might be undermined if the inoculated person has already developed highlevel adenovirus immunity from a previous infection, Chinese researcher­s said in a peer-reviewed paper. Cansino counts Lilly Asia Ventures, backed by US pharmaceut­ical giant Eli Lilly and Co, as its top shareholde­r, according to Refinitiv data.

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