IN WOMEN, FERTILITY AND ORGASM ARE NOT CONNECTED. IN MEN, THEY ARE INSEPARABLE.
WOMEN BEAR THE BURDEN OF CONTRACEPTION ALTHOUGH FEMALE STERILISATION IS PRONE TO INFECTIONS AND WORSE. BUT MANY WOMEN OPT FOR IT BECAUSE THEY ARE WEARY OF FREQUENT PREGNANCIES.
itself (planning replaced welfare).
“After that, nobody was willing to touch this (vasectomy) with a barge pole,” says a public health expert working with the Ministry of Health and Family Welfare who spoke on the condition of anonymity. The problem with the vasectomy, Guha explains, is that it’s permanent. It blocks sperm forcing the body to produce antibodies that destroy the excessive build-up, which brings down the sperm count. The longer a vasectomy lasts, the lesser the chance of reversing its effects.
Guha and his students invented a molecule that took the form of a transparent , gooey liquid. When injected into the two tubes leading to the penis, it takes root like a spider web but firmer. The sperm isn’t blocked because it can pass through the gaps. But, in the process, the gel destroys vital membranes that enable the sperm to fertilise the egg. A second reversible injection, yet to be tested on humans, will dismantle the molecular web.
RISUG attracted interest from pharma companies but it waned — as a one-time, affordable procedure it offers low margins. And in countries like India, where the demand for family planning is huge, the biggest buyer is often the government. Both Pfizer and Bayer told HT male contraceptives are not a priority currently. The last few attempts, including by Bayer in the early 2000s, made little headway.
Guha licensed the RISUG technology to a US-based non-profit, Parsemus Foundation, that is developing the drug for the non-Indian market. Executive director Linda Brent said in an email that the drug, renamed Vasalgel, has a new formulation to suit regulatory standards in the US and Europe. It’s being tested on animals.
She believes money, not demand, is a challenge for male contraceptives, which are usually funded by governments or nonprofits. Parsemus’ surveys, she said, show that some men “wish to relieve their partners of the burden of birth control,” while many want a male contraceptive so they “have direct control over whether they become fathers.”
So why has there been no male contraceptive? Some of it is pure biology: it’s hard to block the millions of sperm that are produced every day. Any one of them can fertilise an egg. “It’s easy to mess around with ovulation,” says Ruma Satwik, a reproductive medicine specialist at Delhi’s Gangaram Hospital. “Egg production is a very, very, very, delicate process.” Ten different hormones have to do their job just right to produce an egg. And they get just one chance every month. Stress, diet or any sort of hormonal imbalance can interrupt this: that’s what birth control pills and intrauterine devices (IUDs) do.
Satwik’s most vivid memory of her stint running a primary health centre (PHC) in rural Maharashtra is meeting the District Health Officer, a short, dark, kindly man in cotton trousers and a shirt. The year was 2000. India’s population had crossed the one billion mark.
And the pressure was on: PHCs had to meet their “targets”, recorded in a ruled register, for IUDs, birth control pills, condoms and, most of all, female sterilisation.
Every month, Satwik would assemble along with 50 other doctors from the district and answer the same question: Tum che kithi? (How many?) “If she (a woman) was still menstruating, she was a candidate,” Satwik says. The question was largely about female sterilisation, which has remained the go-to form of family planning for successive Indian governments.
A vasectomy is safer because it’s a minor surgery with no side effects. When women undergo sterilisation, the incision is deeper and the chances of an infection, higher. Oral contraceptives like the birth control pill come with side effects; and inserts such as IUDs are not ideal in large, poor countries where women are more susceptible to vaginal infections and doctors aren’t necessarily qualified to perform the procedure.
So why not push vasectomies more? The firm but unfounded fear that male contraception will somehow hamper masculinity and the pleasure of sexual release. “Fertility and orgasm are delinked in women,” Satwik says. “In men they are insepara- ble.” Many men worry that contraceptives that impede their fertility will also interfere with their orgasm.
“Sex power kum ho jaayega (will decrease).” That, health worker Nurjamal Haque says, concerns men when they are asked to consider a vasectomy. Haque is a community advocate in rural Assam’s Barapeta district: he travels across tiny river islands educating people about the merits of family planning. And he’s relentless. He spent nearly three years persuading a single community elder to allow his 32-year-old wife to undergo sterilisation. Until he agreed, Haque couldn’t convince any of the others in the community either.
“Slowly, slowly, change comes but it takes a lot of hard work,” Haque says in a phone interview. Eight years ago, he couldn’t broach the subject in many of these parts; he and his colleagues were routinely harassed for trying. But now staunch community elders have turned “motivators” and some women are coming to the clinic asking for condoms for their husbands. “One day, the way women come on their own, men will also come,” says Haque. “That is my belief.”
The annual reports of advocacy groups such as the Population Foundation, which work with the government on family planning and other health issues, is filled with uplifting stories of persistent efforts that paid off in rural communities; of women who chose their own birth control; of husbands who were eventually convinced; of couples who negotiated and picked what’s best for them.
But there’s also data: of malnourished, anaemic women; of frequent pregnancies; of widening sex ratios. And there are other stories too. “The mothers-in-law are the gatekeepers,” says *Mehak Sharma, a quantitative researcher who has spent hundreds of hours speaking or at least trying to speak to women in remote villages in Uttar Pradesh, Bihar, Rajasthan and Maharashtra. The government’s Accred- ited Social Health Activist (ASHA), Sharma says, has to get past the mother-inlaw. Then, she’ll often find herself talking under the watchful eye of a sister-in-law.
Sharma’s job is to decode the behaviour behind decisions about family planning, among other things. What is the preferred method and why. In poor communities, she says, she often finds that women don’t think they have a choice. “The first kid is supposed to come like that,” says Sharma, snapping her fingers. “I’m married, I have to have kids — what’s there to think or talk about? You don’t make decisions for yourself. It’s intimidating.”
The decision, Sharma says, usually comes from the doctor because there is no dialogue between husband and wife. Even educated men are not necessarily involved in the decision. She recalls a woman in Mumbai telling her she got her IUD removed because it made her husband physically uncomfortable. Sharma couldn’t understand what she meant and the woman couldn’t explain either.
The question that concerns doctors and advocates is this: if men are so reluctant to use condoms or even discuss contraception, will they consent to being injected with a drug that would disarm their sperm?
None of this perturbs Guha. That, he explains, is not his job. “Research and development — that is life,” he says. Once RISUG gets approved, he says, he wants to start working on a version of it for women: the same gel would enter the fallopian tubes and disintegrate the egg.
“There is enough work for me,” he says, chuckling. ” Is he excited that the drug is nearly past clinical trials? Or disheartened that it took this long? After a brief pause, he offers a nugget of wisdom that he inherited from his father: “One should never be happy or sad about anything.”