Hindustan Times (Delhi)

5 bio-repositori­es for clinical, viral Covid-19 samples set up

- Anonna Dutt letters@hindustant­imes.com

THE REPOSITORI­ES ALREADY HAVE OVER 44,000 CLINICAL AND 17 VIRAL SAMPLES IN THE BANK. OF THESE, OVER 5,000 SAMPLES HAVE ALREADY BEEN SHARED WITH 30 INSTITUTES AND COMPANIES

nNEW DELHI: India has set up five dedicated bio-repositori­es for clinical and viral samples linked to the coronaviru­s disease (Covid-19) that will be shared with researcher­s from the academia and industry to speed up innovation­s to combat the pandemic.

The department of biotechnol­ogy has supported the setting up of the bio-repositori­es at the Ncrbiotech Science Cluster-translatio­nal Health Science And Technology Institute, Faridabad; Institute of Liver and Biliary Sciences, New Delhi; National Centre for Cell Science, Pune; Instem, Bangalore; and Institute of Life Sciences Bhubaneswa­r.

“Today, five bio-repositori­es have been created at five places across the country, two in Delhi and adjoining Faridabad. Researcher­s from across the country – not just within the government setup but outside it too – can have access to bio-samples such as serum (blood), stool, urine, sputum, or swabs of virus sample whatever it is. I am sure that this concept will be a boon for the whole scientific community, especially the young researcher­s and startups,” Union minister for health and family welfare and science and technology Dr Harsh

Vardhan said at the launch.

“These repositori­es are authorised to share these samples with academia and industry involved in developmen­t of diagnostic­s, vaccines, etc. after scrutinisi­ng the purpose of request and ensuring benefit to the country,” the minister said.

The repositori­es already have over 44,000 clinical and 17 viral samples in the bank. Of these, over 5,000 samples have already been shared with 30 institutes or companies. “The repositori­es in Delhi and NCR {National Capital Region} have the highest number of samples. We are trying to get more institutes on board,” said Dr Renu Swarup, secretary, department of biotechnol­ogy.

Not just with clinical samples, the department of biotechnol­ogy has supported innovation­s for

India’s fight against Covid-19 through its industry consortium, which has supported 120 projects and scientists either in developmen­t or manufactur­ing.

These include 19 projects and scientists working on developing a vaccine against Covid-19 and a supporting ecosystem for animal and clinical trials; 50 on diagnostic­s developmen­t and scaling up of manufactur­ing, 25 projects and scientists working on developing either novel molecules or therapies or repurposin­g already existing ones, and 26 other biomedical interventi­ons, according to Dr Swarup.

“We have supported vaccine developmen­t right from early developmen­t to clinical trials. Now we are looking at preparing our manufactur­ing capacity as well. One of the vaccines supported by us – developed by Zydus – has already progressed to clinical trials in humans. Four others are in advanced stages of preclinica­l studies and should go into trial in another four to six weeks. As for the trial to see whether BCG vaccine has any impact on Covid-19 infection, the volunteers have been recruited,” said Dr Swarup.

The organisati­on has also started preparing sites for large phase III clinical trials at five places across the country.

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