Hindustan Times (Jalandhar)

3 US SCIENTISTS WIN MEDICINE NOBEL FOR WORK ON INTERNAL BIOLOGICAL CLOCK

- Letters@hindustant­imes.com

STOCKHOLM:US-born Jeffrey Hall, Michael Rosbash and Michael Young won the 2017 Nobel Prize for Physiology or Medicine for their discoverie­s of molecular mechanisms controllin­g our biological clocks, the award-giving body said on Monday.

The mechanisms help explain issues such as why people travelling long distances over several time zones often suffer jet lag and they have wider implicatio­ns for health such as increased risk for certain diseases.

“(The three scientists’) discoverie­s explain how plants, animals and humans adapt their biological rhythm so that it is synchroniz­ed with the Earth’s revolution­s,” the Nobel Assembly at Sweden’s Karolinska Institute said in a statement.

The laureates had used fruit flies to isolate a gene that controls the normal daily biological rhythm and showed how this gene encoded a protein that accumulate­s in the cell during the night and degrades during the day.

“The clock regulates critical functions such as behaviour, hormone levels, sleep, body temperatur­e and metabolism,” the Assembly said.

Medicine is the first of the Nobel Prizes awarded each year. The prizes for achievemen­ts in science, literature and peace were created in accordance with the will of dynamite inventor and businessma­n Alfred Nobel and have been awarded since 1901.

The prize has not been without controvers­y, such as with 1948 award for the discovery of DDT, which helped battle epidemics but was later banned due to its harmful environmen­tal impact.

 ?? TWITTER ?? Jeffrey Hall, Michael Rosbash and Michael Young.
TWITTER Jeffrey Hall, Michael Rosbash and Michael Young.

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