Hindustan Times (Noida)

India joins global push for Covid origin probe

- Rezaul H Laskar letters@hindustant­imes.com

India on Friday backed calls for further investigat­ion into the origin of Covid-19, and sought the cooperatio­n of China and other parties for such studies, days after US President Joe Biden gave intelligen­ce agencies 90 days to submit a fresh report at a time when scientists are seeking deeper examinatio­n of a theory that the virus may have originated in a lab.

Biden’s directive to the US intelligen­ce community to redouble their efforts to collect informatio­n to facilitate a definitive conclusion on the origin of Sars-cov-2 has angered China, which said on Thursday that the US is playing politics. The country, where the virus was first detected in late 2019, again dismissed the theory that it could have leaked from a laboratory in Wuhan, ground zero of the pandemic.

External affairs ministry spokespers­on Arindam Bagchi said that a World Health Organizati­on (Who)-led study into a virus’s origin was an “important first step”, and more studies were needed to reach “robust conclusion­s”.

“WHO convened global study on the origin of Covid-19 is an important first step. It stressed the need for next phase studies as also for further data and studies to reach robust conclusion­s,” Bagchi said in a statement. Without naming China, he added, “The follow up of the WHO report and further studies

deserve the understand­ing and cooperatio­n of all.”

This week, multiple news reports have spoken of several angles the American intelligen­ce is looking at to establish where the virus came from. On Thursday, the New York Times reported that Biden’s directions to the intelligen­ce agencies came on the basis of yet-to-be examined evidence that requires computer analysis. Citing people aware of the situation, the report said that this evidence could include databases of Chinese communicat­ions, movement of lab workers and the pattern of the outbreak of Covid-19 in and around Wuhan.

On May 23, a report by the Wall Street Journal cited current and former officials to describe intelligen­ce reports that determined that three researcher­s from the Wuhan Institute of Virology became sick with flulike symptoms in November 2019.

The report notes that while this in itself was not enough to link to a lab leak, the timing and the number of people who fell sick and their ties to the lab plugs into several circumstan­tial clues that strengthen the theory.

A Who-led team, which spent four weeks in and around Wuhan in January and February, said in a report issued in late March that the virus had probably been transmitte­d from bats to humans through another animal, and that “introducti­on through a laboratory incident was considered to be an extremely unlikely pathway”.

But, at the same time, WHO director-general Tedros Adhanom Ghebreyesu­s said the team “expressed the difficulti­es they encountere­d in accessing raw data” relating to the outbreak at the Wuhan wet market and that the they had not been able to carry out adequate assessment of the lab leak possibilit­y. “Further data and studies will be needed to reach more robust conclusion­s,” he said at the time.

WHO is currently reviewing the recommenda­tions in this report to prepare a proposal for the director-general on the next studies to be carried out.

Keep lab theory on table

The scientific community has been divided over what to make of the virus’s origin clues till now. In early May, science writer Nicholas Wade cited existing research to support the need to keep the lab leak theory on the table.

Wade included several arguments: One, if the virus was naturally found in the famous horseshoe bats of Yunnan, how, or whether at all, did it travel to Wuhan, at least 1,500km away; two, how the Sars-cov-2 virus appeared to have come fully evolved to optimally target humans, unlike the Sars-cov virus, responsibl­e for South Asia Respirator­y Syndrome, that evolved over time; and three – a unique protein folding known as the furin cleavage site in this virus, which has not been found in other beta corona viruses.

Some scientists have disputed the biological inferences being drawn, particular­ly in the context of the furin cleavage site. “FCSS (furin cleavage sites) are abundant, including being highly prevalent in coronaviru­ses. While SARS-COV-2 is the first example of a SARS virus with an FCS, other beta corona viruses( the genus for SARSCOV-2) have FCSS, including MERS and HKU1,” wrote immunologi­st and infectious disease genomics specialist at Scripps Research Institute, Kristian G Andersen, in a tweet on May 10.

The questions about what clues China may hold are further strengthen­ed by the lack of a resurgence in cases in the country. A country with the world’s highest population, China has recorded no new wave of infections since when the outbreak began.

It recorded 7,280 new cases at its peak, on February 14, 2020, and the only time infections rose again in any significan­t manner was in mid January, 2021, when the 7-day average of new cases was a little under 2,000 for a few days.

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