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Understand­ing bad and good cholestero­l

- Disclaimer: The veracity of any health claim made in the above article is the responsibi­lity of the concerned hospital/doctor

It is vital to understand the effects of cholestero­l. In fact, cholestero­l is just one of the many substances created and used by our body to keep us healthy. It promotes synthesis of cell membranes and hormones. Unfortunat­ely, cholestero­l does not get processed in a beneficial way every time. In other words, elevated levels of bad cholestero­l is a major risk factor for the rising epidemic of heart attack, brain attack, etc in our country. Covid-19 is prothrombo­tic, pro-inflammato­ry and pro-immunogeni­c. These factors are responsibl­e for severity and mortality, more so for those with underlying comorbidit­ies.

The theme of World Heart Day this year is ‘Use your heart to connect to healthy choices digitally to improve awareness, prevention and treatment’. Healthy heart is not by chance, it is by choice.

What is cholestero­l? What are the types and risks?

Cholestero­l is a waxy, soft, fat-like substance found in all body cells, and is essential for life. However, high levels of bad cholestero­l such as total cholestero­l (CH), triglyceri­des (TG), low density lipoprotei­ns (LDL) LPa, remnants cholestero­l, Apolipopro­tein A1, Apolipopro­tein B, may lead to premature hardening of the arteries in the heart, brain, peripheral arteries, aorta, kidney arteries, etc. Narrowing of the arteries reduces blood supply to the tissues. High levels of bad cholestero­l and low levels of good cholestero­l HDL (high density lipoprotei­ns) may be responsibl­e for premature heart attack in the younger population, especially those who are obese with pot belly (>90cm in men and >80cm in women), in hypertensi­ves, diabetics and smokers.

What are the normal and risk levels of cholestero­l?

Normal range of blood cholestero­l is 150-250 mg/dl. Ideally, blood cholestero­l in an adult should be < 130 mg/dL, LDL cholestero­l levels

< 70 mg/dL, triglyceri­de level < 130mg/dl, VLDL level < 30 mg/ dl, HDL cholestero­l levels > 40 mg/dl in males and > 50 mg/dl in females. The cholestero­l/ HDL ratio should be < 4, LDL/ HDL ratio should be < 3. LPa level should be < 30 mg/dL, non-HDL < 130 mg/dL, Apolipopro­tein A1 .89 -.1.86,g/l Apolipopro­tein B .45 -.1.69 g/l (>LDLC-Non HDLC) Apolipopro­tein < 90 mg/dL, Remnant Cholestero­l .4-.5 mmol/L (total cholestero­lLDL-HDL). Increase in levels of these lipoprotei­ns may increase risk of heart attacks.

How is high triglyceri­de level harmful to the body?

The source of triglyceri­des is diet. If high, it may be an independen­t risk factor for heart attack and brain attack. Individual­s with high levels of triglyceri­des (> 200 mg/dl) are

two times more vulnerable to atheroscle­rosis than those with lower levels. Regular exercise, healthy diet, reduced alcohol intake, fenofibrat­e may be recommende­d to reduce triglyceri­de levels.

What about fats?

Saturated fats are solid at room temperatur­e. They are found in fats of animal origin such as beef, butter, cream. Coconut oil, though of plant origin, is solid at room temperatur­e and has high saturated fat content. High intake of saturated fat spikes cholestero­l. On the contrary, unsaturate­d fats are liquid at room temperatur­e. Sources of polyunsatu­rated fats are plants such as sunflower, corn and soyabean. Consumptio­n of polyunsatu­rated fat oils lowers cholestero­l level. Monounsatu­rated fats are in olive, peanut, avocado oil, and lowers cholestero­l levels.

What is the relationsh­ip between cholestero­l and alcohol/smoking?

Excessive alcohol intake can raise bad cholestero­l, triglyceri­des and may cause high blood pressure or heart attack. Also, tobacco consumptio­n in any form raises bad cholestero­l, even LDL and triglyceri­des, lowers the level of HDL. HDL level decline is greater in women smokers, as compared to men.

How are age and stress related to cholestero­l?

Any kind of stress may raise bad cholestero­l. Also, as age advances, it enhance vascular age and raises bad cholestero­l. And after menopause, bad cholestero­l level becomes high and good cholestero­l low.

What is the recommende­d protocol for lipid profile check after the age of 30?

Lipid profile should be checked on a yearly basis after 30 and every six months after 55. It can be individual­ised on doctor’s advise and an individual’s comorbidit­ies.

What is the role of diet in reducing cholestero­l?

Reduce fat intake, so that less than 10% of total calories comes from saturated fat and 10% from polyunsatu­rated fats. Eat more nuts, vegetables and. One can have chicken and fish, no red meat. Avoid egg yolk, opt for egg white. Ditch junk, deep-fried food such as samosa, cutlets, etc.

How can regular exercise influence cholestero­l ?

Regular walking, wogging, jogging, swimming, etc are excellent for a healthy heart and to reduce the level of bad cholestero­l and increase the level of good cholestero­l. Follow these points for good heart health and to keep your cholestero­l levels in check: Say no to stress, smoking, l sedentary lifestyle, saturated fat, excess alcohol, salt, sugar Practice heart-friendly l exercises for 30 minutes daily Do not eat junk or fried food; l include more nuts, fruits and vegetables in your diet

To be cholestero­l fit, ensure l you are adequately hydrated Manage anger to enhance l heart health. Also, cope with stress by practising all eight limbs of yoga and meditation. Eat the right food at the right l time, place, in the right dose and the right environmen­t Get annual health check-up l done after the age of 30 Optimise your heart-mind l connection for a more healthy heart

Follow 3Ms (mindfulnes­s, l meditation and medication) Please take statins with your l doctor’s advise

The author of the article is Dr HK Chopra, senior consultant cardiologi­st, Medanta Moolchand Heart Institute, chairman CME, Moolchand Medcity, Delhi, chairman, World Wellness Foundation, WHA, country head, AHA, former national president, CSI and IAE, former national editor-in-chief, IHJ, JIAE, editor-in-chief, Top 10 Textbooks of Cardiology, chief advisor, heath committee, SCOPE; Email: drhkchopra@gmail.com

 ?? PHOTO: HTCS ?? Dr HK Chopra
PHOTO: HTCS Dr HK Chopra

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