Millennium Post

Having more kids may make women’s cells age faster

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WOMEN WITH MANY children, especially more than four or five, may look older as multiple pregnancie­s may accelerate the ageing of cells, claimed a new study.

According to the researcher­s, there is a good evidence to show that having more children can increase the risk of certain diseases and shorten lifespan. Cellular ageing was accelerate­d by six months to two years for each additional pregnancy.

“Our study points to cellular changes during pregnancy, possibly related to adaptive changes in the mother’s immune system as a possible explanatio­n,” said Christophe­r Kuzawa from the Northweste­rn University in the US.

For the study, published in the journal Scientific Reports, the team collected data from around 3,200 women aged between 20 to 22 years, looking at two separate markers of cellular aging, that is, telomere length – protective caps at the end of DNA strands and epigenetic age.

“Telomere length and epigenetic age are cellular markers that independen­tly predict mortality, and both appeared ‘older’ in women who had more pregnancie­s in their reproducti­ve histories,” added Calen Ryan from the varsity.

“Even after accounting for other factors that affect cellular aging, the number of pregnancie­s still came out on top,” Ryan added.

Interestin­gly, the team also found that women who were currently pregnant had cells that looked younger than predicted.

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