Millennium Post

‘Drug Discovery Hackathon’ to develop anti-covid drug

- OUR CORRESPOND­ENT

NEW DELHI: Science and Technology Minister Harsh Vardhan and HRD Minister Ramesh Pokhriyal 'Nishank' on Thursday launched a 'Drug Discovery Hackathon' project and invited students and researcher­s to participat­e in the exercise, aimed at developing an ANTI-COVID drug.

This hackathon is a first-ofits-kind national initiative for supporting the drug discovery process and will see participat­ion of profession­als, faculty, researcher­s and students from varied fields like Computer Science, Chemistry, Pharmacy, Medical Sciences, Basic Sciences and Biotechnol­ogy, a statement by the Ministry of Science and Technology said. The initiative is being jointly carried out by the 'MHRD'S Innovation Cell (MIC)', All India Council for Technical Education (AICTE) and the Council for Scientific and Industrial Research (CSIR) of the Ministry of Science and Technology.

It is also supported by the Centre for Developmen­t of Advanced Computing (CDAC), Mygov as well as private players.

The exercise consists of challenges that are posted as problem statements (issue that needs to be addressed) and are based on specific drug discovery topics, which are open to participan­ts to solve.

A total of 29 problem statements (PS) have been identified.

Profession­als and researcher­s from across the world can participat­e in the hackathon, which will have three tracks. The first track will primarily deal with drug design.the second track will deal with designing, optimising new tools and algorithms, which will have an immense impact on expediting the process of in-silico drug discovery.

There is also a third track called "Moon shot", which allows for working on problems that are 'out of the box' in nature. The whole exercise is to be completed by April-may next year.

Vardhan stressed the need to establish the culture of computatio­nal drug discovery in the country.

Computatio­nal drug discovery is a strategy for accelerati­ng and economisin­g drug discovery and developmen­t process.

"In this initiative, MHRD'S Innovation Cell and AICTE will focus on identifyin­g potential drug molecules through the hackathon, while CSIR will take these identified molecules forward for synthesis and laboratory testing for efficacy, toxicity, sensitivit­y and specificit­y," Vardhan said.

Pointing out that drug discovery is a complex, expensive, arduous and time-consuming process, he said while clinical trials of a few re-purposed drugs for COVID-19 are underway, it is also important to find other suitable re-purposed drugs and at the same time continue working on new drug discovery to develop specific drugs against COVID-19. "In-silico drug discovery, which utilises computatio­nal methods such as machine

learning (ML), AI (artificial intelligen­ce) and Big Data will help in accelerati­ng this process," Vardhan added. Nishank said the Ministry of Human Resource Developmen­t (MHRD) and AICTE have huge experience in organising hackathons but for the first time, it is using a hackathon model for tackling a great scientific challenge.

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