Convalescent plasma for Covid patients not responding to steroids: CDSCO

NEW DELHI: Convalescent plasma may be considered in moderate COVID-19 patients who are not improving despite use of steroids, stated a notice issued by the Central Drugs Standard Control Organisation (CDSCO). The notice was issued on Wednesday in reference to Union health ministry's clinical management protocols for COVID-19 released on June 27. The ministry had allowed use of convalescent plasma (off-label) for treating coronavirus patients in moderate stage of the illness under "investigational therapies". "This is with reference to the clinical management protocols for COVID-19 issued by the Government of India, Ministry of Health wherein, certain therapies are indicated for use as investigational therapies, in which convalescent plasma by plasmapheresis has been indicated as off-label in COVID-19 patients," the CDSCO notice, 'Information on Convalescent Plasma in COVID-19', said. "Convalescent plasma may be considered in patients with moderate disease who are not improving (oxygen requirement is progressively increasing) despite use of steroids," it added. The therapy involves taking antibodies from the blood of a person who has recovered from Covid-19 and transfusing those into a coronavirus-infected patient to help kickstart the immune system to fight the infection.