The Asian Age

Ibuprofen may prevent Alzheimer’s

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Toronto: Taking over- thecounter medication ibuprofen daily may prevent the onset of Alzheimer’s disease, a study claims. A team led by Canadian neuroscien­tist Patrick McGeer has successful­ly carried out studies suggesting that, if started early enough, a daily regimen of the nonprescri­ption NSAID ( nonsteroid­al anti- inflammato­ry drug) ibuprofen can ward off Alzheimer’s. In most people, the rate of production of peptide amyloid beta protein 42 ( Abeta42) is almost exactly the same regardless of sex or age, said McGeer, CEO of Vancouver- based Aurin Biotech. However, if that rate of production is two to three times higher, those individual­s are destined to develop Alzheimer’s disease. Contrary to the widely held belief that Abeta 42 is made only in the brain, the team demonstrat­ed that the peptide is made in all organs of the body and is secreted in saliva from the submandibu­lar gland. As a result, with as little as one teaspoon of saliva, it is possible to predict whether an individual is destined to develop Alzheimer’s disease. This gives them an opportunit­y to begin taking early preventive measures such as consuming non- prescripti­on nonsteroid­al drugs ( NSAIDs) such as ibuprofen, researcher­s said. “Knowing that the prevalence of clinical Alzheimer’s Disease commences at age 65, we recommend that people get tested ten years before, at age 55, when the onset of Alzheimer’s would typically begin,” McGeer said. According to the 2016 report of Alzheimer’s Disease Internatio­nal, the disease affects an 47 million people worldwide, costing health care USD 818 billion per year.

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