The Asian Age

Heavy- period drug can treat brain haemorrhag­e

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Adrug used for heavy periods could benefit patients with strokes caused by dangerous brain bleeds, experts says. Currently, there is no effective drug treatment. A trial in The Lancet found tranexamic acid stemmed bleeding and reduced the risk of death in the early days following a haemorrhag­ic stroke. Although it did not equate to less disability at three months, researcher­s are still hopeful about its use as a stroke therapy, according to a BBC report. Up to a fifth of strokes are bleeds. They account for nearly a half of all stroke deaths worldwide. Those who do survive may be left with debilitati­ng disabiliti­es, including paralysis and difficulty with their speech. How to spot the signs of a stroke before it happens: Carolyn Danby was 32 when she had a stroke. She had been out Christmas shopping at the time. “I felt almost a bit of a head rush,” she says. “I didn't quite feel right. I went to pick up a gift bag with my left hand and I couldn't grasp it. I knew something was wrong. I felt like I was drunk really. My left leg started to drag. I was panicking.” She tried to ask for help, but the words wouldn't come out. “I was trying to say, ‘ Please help me, something is wrong’,” she says. “I could say it in my head, but I just couldn't say it.” An emergency scan at hospital revealed Carolyn had a bleed on her brain. She was offered the option to take part in the tranexamic acid trial and accepted. She still doesn't know if she received the drug itself or a dummy injection, but she has made a good recovery. Half of the 2,325 people who took part in the trial were given tranexamic acid and the other half were given a placebo so that the researcher­s could reliably measure what effect the treatment had. Researcher Dr Nikola Sprigg, from the University of Nottingham, said: “Tranexamic acid is a drug that has been around for a long time. It's effective in other bleeding conditions.” It is already used ( in tablets) for treating heavy periods and ( by injection) for controllin­g dangerous bleeding during childbirth or severe trauma. “In the stroke patients it reduced the amount of bleeding in the brain,” Dr Sprigg said. "It also reduced the amount of people that died in the first week after bleeding, which is the emergency period.” Less bleeding should mean less damage and disability, and fewer deaths. The Stroke Associatio­n, which funded earlier stages of the trial, said: “Currently, treatment for haemorrhag­ic stroke is very limited so we are excited by the findings of this study into bleeding that happens within the brain. We hope there will now be further research into how this cheap drug could be used to potentiall­y save lives .”

◗ A stroke happens when the blood supply to the brain is disrupted, either by a blood clot blocking the supply or a bleed. It’s a medical emergency that needs immediate attention. The sooner someone who is having a stroke receives help, the better their chances of a good recovery. presence of oxygen showed that an even earlier generation ◗ Less bleeding should mean less damage and disability, and fewer deaths. Know the signs of a stroke: Face — has it fallen on one side? Arms — can they be raised? Speech — is it slurred?

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