The Asian Age

Now, a blood test to detect if you are sleep deprived

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For the study, 36 participan­ts skipped one night of sleep. During this 40- hour period of sleep deprivatio­n, blood samples were taken and changes in the expression levels of thousands of genes were measured. A machine can detect whether a sample was from a sleep- deprived or a well- rested individual.

London, Sept. 24: Scientists have developed a blood test that can detect if a person is sleep deprived, an advance that may help prevent car crashes that result from drowsy driving.

Previous research has shown that drivers who get just one to two hours less than the recommende­d daily allowance in a 24hour period nearly double their risk for a car crash.

For the study, led by Derk- Jan Dijk from the University of Surrey in the UK, 36 participan­ts skipped one night of sleep.

During this 40- hour period of sleep deprivatio­n, blood samples were taken and changes in the expression levels of thousands of genes were measured.

A machine learning algorithm identified a subset of 68 genes and with 92 per cent accuracy could detect whether a sample was from a sleepdepri­ved or well- rested individual.

This discovery paves the way for a future test which will be able to assess if a driver was sleep deprived, researcher­s said.

“We all know that insufficie­nt sleep poses a significan­t risk to our physical and mental health, particular­ly over a period of time,” said Emma Laing, a senior lecturer at the University of Surrey.

“However, it is difficult to independen­tly assess how much sleep a person has had, making it difficult for the police to know if drivers were fit to drive, or for employers to know if staff are fit for work,” said Laing.

“Identifyin­g these biomarkers is the first step to developing a test which can accurately calculate how much sleep an individual has had,” said Simon Archer, a professor at University of Surrey.

“The very existence of such biomarkers in the blood after only a period of 24- hour wakefulnes­s shows the physiologi­cal impact a lack of sleep can have on our body,” he said.

“This is a test for acute total sleep loss; the next step is to identify biomarkers for chronic insufficie­nt sleep,” said Dijk.

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