Humans can regrow cartilage in joints

London: Cartilage is slow to repair and its break down leads to osteoarthritis. Scientists have discovered how proteins in the tissue are created· The process is similar to that of salamanders, lizard-like amphibians Humans possess a salamander-like ability to regrow cartilage in joints, contrary to popular belief. Researchers have found potent molecules in the body which encourage the growth of new proteins in the connective tissue. The process is similar to that of salamanders, lizard-like amphibians famed for their remarkable ability to recover from damage to their body. Scientists hope the “inner salamander” may lead to treatments for osteoarthritis, a painful condition that is currently incurable. The findings could even pave the way for treatments which help a human grow their own limb back after injury, the Duke University scientists said. Cartilage that covers bones is worn down in osteoarthritis patients over the years, resulting in the bones rubbing against each other. Cartilage repair is currently very limited because injuries are difficult to heal due to there being no blood supply to the tissue. Treatment for osteoarthritis, which affects around nine million people in the UK and 30million in the US, revolve around lifestyle changes to relieve pain. Experts believe a superficial boost of the molecules may speed recovery, preventing the thinning of cartilage. The proteins are produced at different speeds in hips, knees and ankles, which may explain why osteoarthritis (OA) is most common in hips. Dr Ming-Fend Hsueh looked at the age of proteins in collagen — a main component of cartilage — in 18 tissue samples of people with OA.