The Free Press Journal

Genes linked to happiness, depression found

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How happy we feel about life may be encoded in our genes, according to a new global study that identified genetic variants associated with feelings of well-being, depression and neuroticis­m, says PTI.

The study is one of the largest on the genes involved in human behav- iour. More than 190 researcher­s in 140 institutio­ns in 17 countries analysed genomic data from nearly 300,000 people. How people think and feel about their lives depends on multiple factors, including genes.

"We applied advanced statistica­l analyses and metaanalys­ed, or combined, results across a large number of studies, which is the most powerful way to conduct this type of genetics research," said Alexis Frazier-Wood, assistant professor at the Texas Children's Hospital in US. "We found three genetic variants associated with subjective wellbeing - how happy a person thinks or feels about his or her life," said Frazier- Wood.

"We also found two genes harbouring variants associated with depressive symptoms and 11 genes where variation was associated with neuroticis­m," she said. The genetic variants do not determine whether someone develops depressive symptoms, neu- roticism or has a poor sense of wellbeing, researcher­s said.

"Genetics is only one factor that influences these psychologi­cal traits. The environmen­t is at least as important, and it interacts with the genetic effects," said Daniel Benjamin, associate professor at the University of Southern California Dornsife College of Letters, Arts and Sciences. The informatio­n in this report allows researcher­s to look at possible ways to study these conditions.

"We can start studying the functions of these genes to begin to understand why biological­ly some people are more predispose­d to feel this way than others," said FrazierWoo­d. The study was published in the journal Nature Genetics.

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