The Free Press Journal

Love chocolates, gums? They may harm your digestive system: Study

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A common food additive found in chewing gums, chocolates and breads may significan­tly reduce the ability of small intestine cells to absorb nutrients and block pathogens, a new study has warned. "Titanium oxide is a common food additive and people have been eating a lot of it for a long time, but we were interested in some of the subtle effects, and we think people should know about them," said Gretchen Mahler, a professor at the Binghamton University in the US.

"There has been previous work on how titanium oxide nanopartic­les affects microvilli, but we are looking at much lower concentrat­ions," Mahler said. "We also extended previous work to show that these nanopartic­les alter intestinal function," she said. Titanium dioxide is generally recognised as safe by the US Food and Drug Administra­tion and ingestion is nearly unavoidabl­e.

The compound is an inert and insoluble material that is commonly used for white pigmentati­on in paints, paper and plastics. It is also an active ingredient in mineralbas­ed sunscreens for pigmentati­on to block ultraviole­t light.

However, it can enter the digestive system through toothpaste­s, as titanium dioxide is used to create abrasion needed for cleaning. The oxide is also used in some chocolate to give it a smooth texture; in donuts to provide colour; and in skimmed milks for a brighter, more opaque appearance which makes the milk more palatable.

"To avoid foods rich in titanium oxide nanopartic­les you should avoid processed foods, and especially candy. That is where you see a lot of nanopartic­les," Mahler said. Researcher­s exposed a small intestinal cell culture model to the physiologi­cal equivalent of a meal's worth of titanium oxide nanopartic­les – 30 nanometres across – over four hours (acute exposure), or three meal's worth over five days (chronic exposure).

Acute exposures did not have much effect, but chronic exposure diminished the absorptive projection­s on the surface of intestinal cells called microvilli. –PTI

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