The Free Press Journal

‘Mutation’ is the new threat

Each new infection gives the virus a chance to mutate as it makes copies of itself, threatenin­g to undo the progress made so far to control the pandemic

- MARILYNN MARCHIONE

The race against the virus that causes COVID-19 has taken a new turn: Mutations are rapidly popping up, and the longer it takes to vaccinate people, the more likely it is that a variant that can elude current tests, treatments and vaccines could emerge.

The coronaviru­s is becoming more geneticall­y diverse, and health officials say the high rate of new cases is the main reason. Each new infection gives the virus a chance to mutate as it makes copies of itself, threatenin­g to undo the progress made so far to control the pandemic.

On Friday, the World Health Organisati­on urged more effort to detect new variants. The US Centres for Disease Control and Prevention said a new version first identified in the United Kingdom may become dominant in the US by March. Although it doesn't cause more severe illness, it will lead to more hospitalis­ations and deaths just because it spreads much more easily, said the CDC, warning of "a new phase of exponentia­l growth".

"We're taking it really very seriously," Dr Anthony Fauci, the US government's top infectious disease expert, said Sunday on NBC's "Meet the Press." "We need to do everything we can now...to get transmissi­on as low as we possibly can," said Harvard University's Dr Michael Mina. "The best way to prevent mutant strains from emerging is to slow transmissi­on." So far, vaccines seem to remain effective, but there are signs that some of the new mutations may undermine tests for the virus and reduce the effectiven­ess of antibody drugs as treatments.

"We're in a race against time" because the virus "may stumble upon a mutation" that makes it more dangerous, said Dr Pardis Sabeti, an evolutiona­ry biologist at the Broad Institute of MIT and Harvard.

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